Intermittent Hypoxia, Exercise Recovery, Intermittent Exercise, Rating Exertion Perception, Sleep
Conditions
Keywords
intermittent hypoxia, exercise recovery, intermittent exercise, rating exertion perception, sleep
Brief summary
Exercise retraining improves the prognosis and quality of life of patients with chronic lung or circulatory diseases. However, exercise intolerance may be caused by excessive ventilatory. Exposure to oxygen-replete air reduces this ventilatory overload, improves sleep and enhances responses to exercise. This study examine the impact of the acute manipulation of oxygen availability during inter-exercise recovery period of an intermittent cycling exercise on perceptual responses. this randomized, controlled, study include adult patient with COPD. On separate days, 50 patients with COPD completed four sets of 4-min at 85% of VO2peak intercept by 3-min of passive recovery in two randomized between-sets recovery conditions. Rating exertion perception, gaz exchanges, heart rate, sleep quality and nocturnal heart rate variability were assessed. Hypoxic exposure during inter-repetition recovery phases would reduce the ventilatory load during exercise. What's more, patients would not be forced to perform the sporting gesture in a restricted space or wearing a mask, limiting dyspnea and the perceived difficulty of the effort. Lastly, the induction of hypoxic stress during the re-training session helped to improve patients' sleep.
Interventions
OTHERNormobaric hypoxia
Normobaric hypoxia (inspired oxygen fraction of 12.9%) applied between-sets recovery periods
OTHERnormoxic condition
Between-sets recovery periods under normoxic condition
Sponsors
Centre Hospitalier Universitaire, Amiens
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
40 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* from 40 to 60 years * follow-up in the pneumology unit of CHU Amiens - Picardie * Chronic Obstructive Pulmonary Disease stade II * Body mass index from 20 to 30 kg.m-2 * Tiffeneau index \< 70% of predicted value * FEV1 from 50 to 80% of predicted values * Smoking cessation since at least 1 week * Sedentary or physical active * Affiliate to social security * Written consent
Exclusion criteria
\-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Perception Exertion score with CR10 | day 1 | The modified Borg CR10 RPE scale measures exertion on a scale of 0 (no exertion or resting) to 10 (pushing yourself to the max). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Cardiorespiratory responses to exercise | day 1 | Cardiorespiratory responses to exercise is measured with gaseous exchange volumes |
Countries
France
Contacts
Primary ContactEmeric Thiesset, MD
Outcome results
None listed