Infertility Female, Intestinal Permeability, Mediterranean Diet, Zonulin
Conditions
Keywords
female infertility, serum zonulin, mediterranean diet, clinical pregnancy
Brief summary
The goal of this clinical trial is to learn if mediterranean diet works to treat infertility in women. It will also learn about the initial and end of study zonulin levels of mediterranean diet and control group. The main questions it aims to answer are: * Does mediterranean diet lower the serum zonulin levels of participants? * Does mediterranean diet improves the treatment success of participants with infertility? Researchers will compare mediterranean to a control group to see if diet works to treat infertility. Participants will: * Apply Mediterranean diet or routine diet without energy restriction for 8 weeks * Visit the clinic once every 4 weeks for checkups and tests
Interventions
BEHAVIORALmediterranean diet
All questions of the intervention group, in which behavioural change was expected, were answered by the dietitian throughout the study and compliance with the diet was monitored with food consumption records.
Sponsors
SINEM BAYRAM
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* Being in the range of 18.5-29.9 kg/m2 BMI * Having started infertility treatment
Exclusion criteria
* Having a chronic disease (diabetes mellitus, hypertension, etc.) * Previous ovarian surgery * Being diagnosed with PCOS, endometriosis * Known autoimmune disease * Thyroid disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| intestinal permeability | From enrollment to the end of treatment at 8 weeks | serum zonulin levels |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| infertility outcomes | From enrollment to the end of treatment at 8 weeks | number of eggs collected |
Countries
Turkey (Türkiye)
Outcome results
None listed