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Effect of Neurophysiological Facilitation of Respiration on Blood Gases and Hospital Stay in Children With Pneumonia

Effect of Neurophysiological Facilitation of Respiration on Blood Gases and Duration of Hospitalization in Children With Pneumonia

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07070271
Enrollment
36
Registered
2025-07-17
Start date
2025-08-01
Completion date
2025-12-31
Last updated
2026-09-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pneumonia

Keywords

Pneumonia, Neurophysiological facilitation, Chest physical therapy, Blood gases

Brief summary

The goal of this clinical trial is to investigate the effect of respiratory neurophysiological facilitation techniques on arterial blood gases, the severity of respiratory distress and duration of hospital stay in hospitalized children with pneumonia.

Detailed description

Children who were hospitalized with a clinically and radiologically confirmed diagnosis of pneumonia will participate in this study. Selected Patients will be randomly assigned into two groups of equal number. One group will only receive conventional chest physical therapy program in form of (postural drainage, chest percussion, vibration and suction if needed). The other group will receive conventional chest physical therapy program along with respiratory neurophysiological facilitation techniques in form of (anterior basal lift, intercostal stretch, abdominal co-contraction). All patients will receive the treatment program once a day throughout the hospitalization period until discharge.

Interventions

OTHERRespiratory neurophysiological facilitation techniques

The respiratory neurophysiological facilitation techniques in form of (anterior basal lift, intercostal stretch, abdominal co-contraction) once a day throughout the hospitalization period until discharge.

conventional chest physical therapy program in form of (postural drainage, chest percussion, vibration and suction if needed) once a day throughout the hospitalization period until discharge.

Sponsors

Asmaa Ahmed Abd El-samad
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
6 Months to 2 Years
Healthy volunteers
No

Inclusion criteria

* Children of both sexes, with age ranged from 6 months to 2 years old. * All children diagnosed with pneumonia. * All children should be vitally stable during the study period.

Exclusion criteria

* Medically unstable children. * Children with uncontrolled convulsions. * Children with Osteopenia.

Design outcomes

Primary

MeasureTime frameDescription
Arterial blood gasesAt baseline (after enrollment and before the first chest physiotherapy session) and on day 5 after completing the fifth session, assessed within 5 days of enrollmentBlood gas analysis is a commonly used diagnostic tool to evaluate the partial pressures of gas in blood and acid-base content. The blood sample is collected from the radial artery or the femoral artery.
Duration of hospitalizationFrom the date of hospital admission until the date of discharge, up to 20 days
The severity of respiratory distressAt baseline (after enrollment and before the first chest physiotherapy session) and on day 5 after completing the fifth session, assessed within 5 days of enrollmentUsing the Pediatric Respiratory Severity Score to assess respiratory rate, wheezing, accessory muscle use, SpO2, and feeding difficulties. Each component was given 0 or 1 point and the total score was classified as mild (0-1 points), moderate (2-3 points), or severe (4-5 points)

Countries

Egypt

Contacts

PRINCIPAL_INVESTIGATORAsmaa Ahmed Abd El-samad, master's degree

Cairo University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 18, 2026