Breast Cancer
Conditions
Keywords
nipple-sparing mastectomy
Brief summary
In this study the investigators investigate the oncological outcomes of minimal access nipple sparing mastectomy compared with conventional nipple sparing mastectomy for the treatment of breast cancer
Detailed description
A retrospective analysis of a prospectively collected database was conducted from single institute to compare the oncologic outcomes of MA-NSM versus C-NSM. The clinical results and oncologic outcome (margin involved rate, local recurrence and overall survival) were compared between groups. To prevent bias, a case control approach was conducted with propensity score matching (PSM) method.
Interventions
None listed
Sponsors
Changhua Christian Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Healthy volunteers
No
Inclusion criteria
* primary operable breast cancer and had undergone NSM
Exclusion criteria
* had metastatic disease, non-malignant breast disease cases, bilateral breast cancer cases, recurrent breast cancer as well as male breast cancer cases and patients who did not undergo NSM
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| local recurrence | 10 years | local recurrence |
| distant metastasis | 10 years | distant metastasis |
| disease free survival | 10 years | disease free survival |
| overall survival | 10 years | overall survival |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| intra-operative blood loss | during surgery | intra-operative blood loss |
| post-operative complications | 30 days post-operatively | post-operative complications |
| operative duration | during surgery | operative duration |
Outcome results
None listed