Brain Ischemia, Magnetic Resonance Imaging, Outcome Assessment (Health Care), Prognosis, Stroke, Ischemic, Thrombectomy, Thrombolytic Therapy
Conditions
Brief summary
This study, called TARGET-ASPECT, looks at patients who had a type of stroke called acute ischemic stroke and were treated with clot-busting medicine and a procedure to remove the clot. Even with these treatments, about half of patients don't fully recover. The study aims to see if certain brain imaging scores, especially when combined, can better predict how well patients will recover 90 days after their stroke and if their blood vessels reopen successfully. The study will include 152 patients and last about 9 months. The goal is to find easy and reliable tools that doctors can use to make better treatment decisions.
Interventions
None listed
Sponsors
Study design
Eligibility
Inclusion criteria
: * Patients aged 18 years or older * Confirmed acute ischemic stroke on imaging * Treated with both thrombolysis and thrombectomy * Clinical follow-up data available at 90 days (mRS score)
Exclusion criteria
: * Primary hemorrhagic stroke * Early death or loss to follow-up without evaluation * Poor-quality imaging that cannot be analyzed
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Favorable functional outcome defined as a mRS score of 0 to 2 at 90 days | 90 days |
Countries
France