Hyperpigmentation
Conditions
Keywords
Lip hyperpigmentation, Seaweed, Antera3D, Lip care
Brief summary
The goal of this clinical trial is to evaluate the efficacy of the novel lip product containing Caulerpa lentillifera extract on the appearance and perception of dark lips in Thai adults aged 18 to 60 who report concerns about darkened lips. The main question it aims to answer is: Can the novel lip product containing C. lentillifera extract will significantly improve the appearance and perception of dark lips in Thai adults by reducing hyperpigmentation compared to baseline measurements? Participants will apply the lip product twice a day, in the morning after breakfast and before bedtime, and refrain from using other lip products throughout the clinical trial period (7 days). Researchers will compare the result to baseline measurements
Interventions
OTHERLip product
Lip product containing Caulerpa lentillifera extract
Sponsors
Chulalongkorn University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Understand the study protocol and provide informed consent after being informed of potential risks and benefits. * Refrain from using any other lip products, including lipstick, lip gloss, or lip conditioners, during the study period.
Exclusion criteria
* Have a known allergy or sensitivity to cosmetic products or Caulerpa lentillifera. * Are on medication one month prior to study commencement. * Exhibit lip abnormalities such as malformation, inflammation, swelling, or sores.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline in improving lip hyperpigmentation | Baseline and 7 days | Lip hyperpigmentation is assessed using Antera3D at baseline and 7 day after usage |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline in improving lip dryness | Baseline and 7 days | Lip dryness is assessed using Fotofinder system at baseline and 7 day after usage |
| Subjective assessment by participants | Baseline, day 1, and day 7 | Participants' evaluations will be collected through an online self-reported questionnaire. Subjective perceptions of lip color and dryness will be assessed using a 0-10 numerical darkness and dryness scale. Additionally, a satisfaction rating questionnaire will be administered to assess participant satisfaction with their lip appearance and the lip product on day 1 and day 7. The questionnaire will evaluate six key aspects of product performance; 1. Overall satisfaction 2. Effectiveness in hydration and moisturization 3. Improvement in lip color and texture 4. Ease of use and packaging design 5. Sensory attributes such as texture and scent 6. Occurrence of any adverse reactions |
Countries
Thailand
Outcome results
None listed