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Amnioreduction in Polyhydramnios

Benefits and Risks of Amnioreduction for Management of Pregnant Women With Polyhydramnios

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07067593
Enrollment
28
Registered
2025-07-16
Start date
2025-08-31
Completion date
2026-02-28
Last updated
2025-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polyhydramnios

Keywords

Amnioreduction, Polyhydramnios

Brief summary

The aim of this work is to review the indications, procedural complications and outcomes of amnioreduction in pregnancies complicated by polyhydramnios.

Detailed description

Polyhydramnios is the presence of excessive amniotic fluid in the amniotic sac and it's prevalence reaches 2% of all pregnancies . Polyhydramnios is diagnosed based on ultrasound criteria, as an amniotic fluid index (AFI) \>25 cm or maximal vertical pocket \> 8 cm . There is a recognized association of polyhydramnios and adverse pregnancy outcomes, including perinatal death, fetal abnormality and preterm birth . Management of the pregnancy can be problematic, particularly in severe cases, due to issues surrounding maternal discomfort and the risk of preterm birth. Amnioreduction, widely used in the management of polyhydramnios, is an option available to palliate maternal symptomatology and potentially prolong the pregnancy . Previous publications have shown a reduction in the risk for premature rupture of membranes and preterm labor decrease, placental perfusion improvement, and relief of maternal discomfort following amnioreduction

Interventions

None listed

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Healthy volunteers
No

Inclusion criteria

* Pregnant women 20- 38 weeks * Patients with polyhydramnios

Exclusion criteria

* Lethal fetal anomalies * Pre labor rupture of membranes * Placental separation * Chorioamnionitis

Design outcomes

Primary

MeasureTime frameDescription
Gestational age at delivery4 monthsDetermine Gestational age at delivery in polyhydramnios patients . Increased age is good.
Rate of PROM4 monthsNumber of cases developed PROM

Countries

Egypt

Contacts

Primary ContactMohamed Fekry, PhD
mohamedbeethoven2040@gmail.com0882312388

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026