Atopic Dermatitis
Conditions
Brief summary
Twenty-five patients with atopic dermatitis applied lidocaine cream plus a moisturizer to the right limb and lidocaine cream alone to the left limb, twice daily for four weeks.
Interventions
DRUGControl lidocaine cream
lidocaine cream alone
DRUGExperimental lidocaine cream + moisturizer cream
lidocaine cream + moisturizer cream
Sponsors
First Affiliated Hospital of Kunming Medical University
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
1. Male or female patients aged 18-65 years. 2. Clinical diagnosis of atopic dermatitis according to the 2020 Guidelines for the Diagnosis and Treatment of Atopic Dermatitis in China (symmetrical eczematous lesions for ≥6 months plus personal/family atopy history or elevated IgE/eosinophilia). 3. Voluntarily signed informed consent form.
Exclusion criteria
1. Active heart, liver, kidney, or other serious systemic illness. 2. History of viral or bacterial infection within 1 month prior to enrollment. 3. Immunocompromised patients or those receiving systemic immunosuppressive therapy. 4. Known allergy to lidocaine, moisturizer components, or any study-related topical agents. 5. Pregnant or breastfeeding women. 6. Use of topical corticosteroids or calcineurin inhibitors within 2 weeks prior to enrollment.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| change in SCORAD (SCORing Atopic Dermatitis) from baseline | 4 weeks | For each patient, a score will be obtained at baseline, after 4 weeks. The minimum score is 0 (best outcome) and the maximum score is 103 (worst outcome). |
Countries
China
Outcome results
None listed