Chronic Prostatitis (CP)
Conditions
Keywords
Chronic prostatitis, ESWT, Phytotherapy, LUTS
Brief summary
to compare the efficacy and safety of ESWT combined with phytotherapy, ESWT alone and phytotherapy alone in treatment of chronic prostatitis.
Detailed description
In this study the investigators will conduct a Prospective randomized clinical trial, patients will be randomized to 3 groups where they will use use radial waves device (INTELECT RPW SHOCKWAVE) By Chattanooga for ESWT. Another group will receive Phytothyrapy that will be capsules containing powder extract of saw palmetto , tomato , uvaursi , pygeum and pumpkin. while the last group will receive both.
Interventions
DEVICEESWT
Transperineal Shockwaves that are applied once a week for 8 consecutive weeks with a protocol of 3000 pulses each; pressure: 1.8-2.0 bar and a frequency of 10 Hertz (Hz)
DRUGPhytotherapy that contains powder extract of (saw palmetto , tomato , uva ursi , pygeum and pumpkin
1capsule tob be taken twice daily for one month.
Sponsors
Ain Shams University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Perineal or pelvic pain or discomfort of at least 3 months * NIH-CPSI total score greater than 15, * Negative semen cultures for bacteria.
Exclusion criteria
* Evidence of bacteria in seminal culture tests, * Urinary stones, * Uncontrolled coagulopathy, * Chronic bacterial prostatitis, * Bladder and prostate cancer, * Medications that could affect lower urinary tract function during the last month * Serum prostate-specific antigen levels (PSA) more than 4 ng/mL * History of prostate surgery or radiotherapy * Perineal anatomical abnormalities * Neurological abnormalities. * Previous extensive pelvic injuries
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| compare the degree of symptoms relief between the three groups | pre intervenon, at 4 and 8 weeks post intervention and at 2 and 4 months post intervention. | using National Institutes of Health-developed Chronic Prostatitis Symptom Index (NIHCPSI) that will be filled by the patients pre and post intervention at 4 weeks and 8 weeks, 2 and 4 months. It comprises three key domains: pain (scored from 0 to 21), urinary symptoms (0 to 10), and the impact on quality of life (0 to 12), with a total score range spanning from 0 to 43. Higher scores reflect more severe symptoms and a worse overall outcome, while lower scores indicate milder symptoms and a better clinical picture. Severity is typically interpreted as mild (0-9), moderate (10-18), severe (19-31), and very severe (32-43), making the scale valuable for both diagnosis and monitoring treatment progress. |
Countries
Egypt
Contacts
Primary ContactYounan R. Samir, lecturer
Backup ContactWalid E. Mousa, Assisstant Professor
Outcome results
None listed