Skip to content

Effects of Meal Energy Density on Body Measures and Metabolism in Women

Effects of Meal Energy Density on Anthropometric Measurements, Some Metabolic Parameters, And Subjective Appetite in Women

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07066618
Enrollment
28
Registered
2025-07-15
Start date
2023-11-15
Completion date
2024-03-25
Last updated
2025-07-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Appetite Regulation, Circadian Rhythm, Meal Timing, Metabolic Health, Obesity, Overweight

Keywords

circadian rhythm, appetite, Meal Timing, obesity, Glucose Metabolism

Brief summary

This study investigates whether the timing of energy intake during the day-specifically consuming more calories at breakfast or at dinner-affects body measurements, blood sugar levels, cholesterol, and feelings of hunger in women who are overweight or obese. A total of 28 women participated in the study and were randomly assigned to one of two diet plans: one group consumed half of their daily calories at breakfast, while the other consumed them at dinner. Both groups followed a calorie-restricted diet for six weeks. The goal of this research is to understand whether eating more in the morning rather than in the evening leads to better outcomes for weight control and metabolic health. Findings from this study may help health professionals make more effective meal timing recommendations for weight loss and improving blood sugar regulation.

Interventions

BEHAVIORALBreakfast-Loaded Hypocaloric Diet

Participants in this group consumed a hypocaloric diet in which 50% of daily energy intake was provided at breakfast, 35% at lunch, and 15% at dinner. Meal times were standardized as follows: breakfast (7:00-9:00), lunch (12:00-14:00), and dinner (18:00-20:00). The diet was individually tailored and provided 20% fewer calories than the participants' total energy expenditure. Macronutrient distribution followed recommended guidelines: 45-60% carbohydrates, 10-20% protein, and 20-35% fat.

BEHAVIORALDinner-Loaded Hypocaloric Diet

Participants in this group consumed a hypocaloric diet in which 15% of daily energy intake was provided at breakfast, 35% at lunch, and 50% at dinner. Meal times were standardized as follows: breakfast (7:00-9:00), lunch (12:00-14:00), and dinner (18:00-20:00). The diet was individually tailored and provided 20% fewer calories than the participants' total energy expenditure. Macronutrient distribution followed recommended guidelines: 45-60% carbohydrates, 10-20% protein, and 20-35% fat.

Sponsors

Melike Nur Eroğlu
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Age
20 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

* Women aged 20-45 * BMI ≥25 kg/m² * Regular menstrual cycle * No chronic disease or medication use * PSQI ≤5 (Good sleep quality)

Exclusion criteria

* Pregnancy or lactation * Gastrointestinal or metabolic disorders * Shift workers, sleep disorders * Medication affecting metabolism * Weight change \>4.5 kg in last 6 months

Design outcomes

Primary

MeasureTime frame
Change in fasting blood glucoseBaseline to Week 6

Secondary

MeasureTime frame
Change in hip circumferenceBaseline to Week 6
Change in HDL cholesterolBaseline to Week 6
Change in HbA1cBaseline to Week 6

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026