Primary Knee Osteoarthritis
Conditions
Brief summary
Knee osteoarthritis (OA) is a chronic and progressive joint disease characterized by the degeneration of articular cartilage, subchondral bone sclerosis, and the formation of osteophytes. This condition leads to joint pain and stiffness, negatively affecting individuals' quality of life. Joint stiffness, decreased quadriceps strength, and impaired proprioceptive sensation result in functional limitations. Due to these symptoms, individuals experience difficulties in performing daily activities such as rising from a chair, walking, and climbing stairs. The aim of this study is to evaluate the effects of balance, and muscle strength on functional capacity in patients with knee osteoarthritis.
Detailed description
In knee OA, structural changes in the cartilage and the formation of peripheral osteophytes contribute to joint stiffness and a reduction in the range of motion, which adversely affects physical function, particularly in older adults. Activities such as stair climbing, sitting and standing, and walking require the contribution of core muscles as well as lower extremity muscles, particularly the knee extensors. In knee OA, there is a reported decrease in lower extremity muscle strength, especially in the quadriceps femoris muscle, which further impairs functional activities in the advanced stages of the disease. Arthritic damage to joint mechanoreceptors in osteoarthritis leads to a decline in motor control and proprioceptive sensitivity. These sensorimotor deficits result in decreased stability and impaired balance function. Additionally, reduced muscle strength can hinder neuromuscular control, leading to postural instability and an increased risk of falls, especially in older patients. Identifying the factors that contribute to the decline in functional capacity is crucial for planning appropriate exercise programs. The aim of this study is to evaluate the effects of balance, and muscle strength on functional capacity in patients with knee osteoarthritis.
Interventions
None listed
Sponsors
Bezmialem Vakif University
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
FEMALE
Age
45 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Primary knee osteoarthritis
Exclusion criteria
* Previous surgery in the lower extremity * Neuromuscular disease * Vestibular pathology * Physiotherapy intervention or intra-articular injection within the last 6 months
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Muscle strength | Baseline | Muscles strength measurement with 5 time sit-to-stand test |
| Balance | Baseline | Biodex Balance System will be used for postural stability evaluation. Lower scores indicate better stability and higher scores mean poor balance. |
| 6-minute walk test | Baseline | Walking distance will be measured |
| Stair climb test | Baseline | Test completion time will be evaluated |
| Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) | Baseline | Function subscale consisting of 17 items will be used for evaluation. Higher scores indicate greater functional limitation. |
Countries
Turkey (Türkiye)
Contacts
PRINCIPAL_INVESTIGATORKubra Alpay, PhD
Bezmialem Vakif University
Outcome results
None listed