Autonomic Reactivity, Biobehavioral State, Oxytocin, Sonic Augmentation Technology
Conditions
Brief summary
The goal of this clinical trial is to explore possible benefits and mechanisms through which listening to music enhanced with Sonic Augmentation Technology (SAT) can improve health and wellness. The main goals of the study are: * To examine the immediate effects of listening to the augmented music. * To identify individual characteristics that influence the immediate effects of listening to the augmented music. Participants will: * Complete the online pre- and post-surveys. * Provide pre- and post- music saliva samples (1.5mL). * Listen to the full 15-minutes music session via over-ear headphones.
Detailed description
The purpose of the current study is to explore the effects of listening to 15-minutes of sonic augmented music on subjective feelings of calmness and autonomic state. Specific Aims: Specific Aim 1: To investigate whether pre-intervention measures of current functioning relate to the overall functioning of the participants. •The investigators will examine measures of autonomic reactivity to prior mental health and medical adversity, embodiment, and emotional and physical health. Specific Aim 2: To identify the immediate effects of listening to the music •The investigators will explore whether listening to the music leads to improvements in the functioning. First, the investigators will compare the participants who listened to the SAT enhanced music to the participants who listened to the Mozart composition (control). Specific Aim 3: To identify individual characteristics that influence the effectiveness of listening to the SAT music immediately •The investigators will explore the impact of specific vulnerability and resiliency factors (e.g., prior mental and medical adversity) on how well participants benefit from listening to the music immediately. Specific Aim 4: To investigate levels of oxytocin after listening to the music. •The investigators will explore whether listening to SAT enhanced music leads to changes in oxytocin. Specifically, we will compare the levels of salivary oxytocin before and after the intervention in two groups: participants who listen to 15 minutes of the Mozart theme and participants who listen to 15 minutes of the augmented theme. Experimental design * The participants will be randomly assigned to either the augmented music group or the control group featuring a Mozart composition. * Augmented music group: The music is augmented by embedding the natural rhythms of bodily functions (e.g. breathing, heart rate variability, vascular tone, etc) that signal the body to calm. * Control group: The selected Mozart composition consists of: Composition Eine kleine Nachtmusik, K. 525 (5 minutes 30 seconds), Andante from Piano Concerto No. 21, K. 467 (6 minutes 30 seconds), and Ave verum corpus, K. 618 (3 minutes). This composition is structured to serve as emotionally immersive, musically coherent control conditions in a 15-minute experimental paradigm. * The control group will listen to 15 minutes of control music, and the augmented group will listen to 15 minutes of augmented music. * At pre- and post-, the participants will complete online self-report surveys and provide 1.5mL of saliva. * Between-subject analyses will compare those who listened only to the augmented 15-minute music sample and those who listened to the control 15-minutes of music to determine if those who listened to the augmented music exhibit greater changes than those who did not. Subject analyses will determine the potential benefits of listening to music for all participants.
Interventions
BEHAVIORALAugmented Theme
The music is augmented by embedding the natural rhythms of bodily functions (e.g. breathing, heart rate variability, vascular tone, etc) that signal the body to calm.
BEHAVIORALMozart Theme
The selected Mozart composition consists of: Composition Eine kleine Nachtmusik, K. 525 (5 minutes 30 seconds), Andante from Piano Concerto No. 21, K. 467 (6 minutes 30 seconds), and Ave verum corpus, K. 618 (3 minutes).
Sponsors
University of Florida
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Subject)
Masking description
Participants will be randomly assigned via a random number generator to either the augmented group or the control group. The participant will be blinded to the group they are assigned to.
Intervention model description
Participants will be randomly assigned to the augmented or control music group. Both groups will complete a pre-survey and provide a saliva sample. Following the 15-minutes of music, participants will provide a saliva sample and complete a post-survey.
Eligibility
Sex/Gender
ALL
Age
18 Years to 89 Years
Healthy volunteers
Yes
Inclusion criteria
* Between the ages of 18 and 89 * Proficient in English * Employed at UF Health Jacksonville
Exclusion criteria
•Over the age of 89
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Assessing the Impact of Autonomic Reactivity using the Body Perceptions Inventory Short Form | Baseline | This 20-item measure is scored on a 5-point Likert scale (never = 1, occasionally = 2, sometimes = 3, usually = 4, always = 5). Items are summed to determine total autonomic reactivity score, with the higher scores indicating greater autonomic reactivity |
| Assessing the Impact of Adversity History on the Effectiveness of Listening to Music | Baseline | This measure assesses the impact of six types of traumatic experiences (childhood adverse experiences, childhood maltreatment, intimate partner maltreatment, other person maltreatment, life-threatening situations, sudden losses, and person health situations). Each item is scored on a 5-point Likert scale (did not occur = 0, occurred and no impact on my life = 1 to big impact on my life = 4). Items are summed to determine total impact scores. |
| Measuring Change in subjective feelings of calmness and autonomic state using the Benefits List | From baseline through study completion, an average of 90 minutes | This 12-item measure, which assesses subjective feelings of calmness and autonomic state was created for this study. |
| Assessing the Impact of anxiety on the Effectiveness of Listening to Music using the GAD-7 | Baseline | This 7-item measure assesses the severity of generalized anxiety symptoms. It is scored on a 4-point Likert scale (not at all = 0, several days = 1, more than half the days = 2, nearly every day = 3). The items are summed to calculate the total anxiety score, with higher scores indicating more severe anxiety symptoms. |
| Assessing the Impact of depression on the Effectiveness of Listening to Music using the PHQ-8 | Baseline | This 8-item measure assesses the severity of depressive symptoms. It is scored on a 4-point Likert scale (not at all = 0, several days = 1, more than half the days = 2, nearly every day = 3). The items are summed to determine the total depression score, with higher scores indicating greater severity of depressive symptoms. |
| Assessing the Impact of PTSD on the Effectiveness of Listening to Music using the PCL-5 | Baseline | This 8-item measure assesses the severity of depressive symptoms. It is scored on a 5-point Likert scale (not at all = 0, a little bit = 1, moderately = 2, quite a bit = 3, 4 = extremely). The items are summed to determine the total PTSD score, with higher scores indicating greater severity of PTSD symptoms. |
| Assessing the Impact of Moral Injury on the Effectiveness of Listening to Music using the Moral Injury Events Scale | Baseline | This 6-item measure assesses the level of agreement about the occurrence and anguish of moral injury (asked as two separate questions) experienced by participants themselves (self moral injury or Self MI) and observed by participants in others (others moral injury or Others MI). It is scored on a 5-point Likert scale (strongly disagree = 1, Moderately Disagree = 2, 3 = disagree, 4 = agree, 5 = moderately agree, 6 = strongly agree). |
Countries
United States
Contacts
PRINCIPAL_INVESTIGATORLourdes P. Dale, PhD
University of Florida
Outcome results
None listed