Dentofacial Deformities, Edema, Pain
Conditions
Keywords
dentafacial deformities, edema, pain
Brief summary
Lymphatic drainage massage is one of the most essential techniques for reducing edema. It is a very gentle, monotonous, slow, rhythmic massage applied to the skin's surface. This technique accelerates the flow of lymphatic fluid, minimizing swelling and providing relief. Frequently used after orthognathic surgery, lymphatic drainage massage helps reduce edema, enhancing patients' postoperative comfort.
Detailed description
Melatonin, a hormone produced by the pineal gland, is a neurochemical substance that functions in harmony with the body's natural rhythm. In addition to its presence in the brain, melatonin can also be found in the retina, bone marrow, intestines, skin, and various blood cells. Conditions such as insomnia or jet lag may benefit from melatonin supplements. Beyond its role in improving sleep quality, melatonin also contributes to regulating the immune system, body temperature, blood pressure, and cortisol hormone levels. Another important function of melatonin is its powerful free radical-scavenging ability. It can neutralize both reactive oxygen species and reactive nitrogen species. Due to its strong antioxidant properties, several studies have investigated its effects on pain and edema. Research has shown that preoperative and postoperative melatonin administration can reduce postoperative pain and accelerate sensory recovery through its antioxidant effects.
Interventions
OTHERno intervention
this group patients receive any medication for edema control.
A total of 10 sessions of lymphatic drainage massage will be applied to this group of patients, starting from the 2nd postoperative day, with 2 sessions per week.
DIETARY_SUPPLEMENToral melatonin tablet
In this group of patients, the first dose of 10 mg oral melatonin tablet will be given one day prior to the operation, and the patients will continue taking the tablet daily for a total of 21 days.
COMBINATION_PRODUCTboth melatonin and lymphatic drainage
In this group of patients, a total of 10 sessions of lymphatic drainage massage will be applied starting from the 2nd postoperative day, with 2 sessions per week, while the first dose of 10 mg oral melatonin tablet will be administered one day prior to the operation, and the patients will continue taking the tablet daily for 21 days.
Sponsors
Bezmialem Vakif University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
16 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
1. Patients with dentofacial deformities who are planned to undergo orthognathic surgery 2. Patients who have not previously undergone orthognathic surgery 3. Patients with no systemic diseases
Exclusion criteria
1. Presence of systemic diseases affecting general health 2. Presence of malignant disease in the head and neck region 3. Patients who have previously undergone orthognathic surgery 4. Patients with any bleeding disorders 5. Patients with cardiovascular disease who are under anticoagulant or antiplatelet therapy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative edema assessment | 1month | Postoperative edema measurements will be taken after the patient is anesthetized before surgery and on the 1st, 3rd, and 7th postoperative days. Before the surgery, the gonion and tragus will be marked with methylene blue, and the distance between the gonion-lateral canthus and tragus-labial commissure will be measured and recorded using a thread. Measurements will be repeated on postoperative days 1, 3, 7, 14, 21, and 28 and recorded in the evaluation form. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| pain assessment | 1 month | VAS assessment will be performed on all days when edema measurements are taken for pain evaluation. |
Countries
Turkey (Türkiye)
Outcome results
None listed