Training in Combination With Non-invasive Brain Stimulation

Non-invasive Brain Stimulation to Enhance the Effects of Training in Healthy Old and Patients With Focal Brain Lesions

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07059533

Acronym

TrainStim

Enrollment

Registered

2025-07-10

Start date

2017-03-31

Completion date

2025-01-31

Last updated

2025-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Motor Skill Acquisition in Healthy Older Adults

Keywords

Non-invasive brain stimulation, Transcranial direct current stimulation

Brief summary

The goal of this study is to investigate the impact of non-invasive brain stimulation on motor skill acquisition in healthy individuals. Participants performed a motor task with non-invasive brain stimulation applied over the area of the brain where movements were controlled. The study compared motor skill performance between with the active stimulation and the placebo stimulation.

Detailed description

This study implemented a randomized, double-blinded, and sham-controlled design, investigating the effects of non-invasive brain stimulation on motor skill acquisition in healthy individuals.

Interventions

OTHERVerum

anodal transcranial direct current stimulation: 20 minutes of stimulation with 1 mA (ramp-up/ramp-down times of 8 seconds)

OTHERPlacebo

anodal transcranial direct current stimulation with 40 seconds of stimulation delivered at the beginning of training (with 8 seconds ramp-up and 5 seconds ramp-down times)

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

BASIC_SCIENCE

Masking

DOUBLE (Subject, Investigator)

Intervention model description

We randomly assigned participants to receive either real or placebo stimulation

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* age equals to or over 18 years old * absence of major neurological, psychiatric and physical impairment, with normal or corrected to normal vision * right handed * in good general health

Exclusion criteria

* professional musicians/stenotypist * unable to consent * unable to perform the task as required (instructions and setup) *

Design outcomes

Primary

Measure	Time frame	Description
Motor performance	From the start of the practice to the end of training at 5 days (and follow up on the 10th day and 60th day)	Replication of a nine-digit sequence displayed on a screen, as quickly and as accurately as possible, using the left hand

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026