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Non-Invasive Techniques to Maintain Neck Flexion and Reduce Anastomotic Tension After Tracheal Resection

Non-Invasive Techniques to Maintain Neck Flexion and Reduce Anastomotic Tension After Tracheal Resection

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07059195
Enrollment
30
Registered
2025-07-10
Start date
2025-06-30
Completion date
2027-06-30
Last updated
2025-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Maintain Neck Flexion and Reduce Anastomotic Tension After Tracheal Resection

Brief summary

Tracheal surgery represents a relatively recent advancement in the field of thoracic surgery. The trachea has unique anatomical and physiological challenges that historically rendered surgical manipulation both risky and limited. Early interventions involving the trachea were primarily restricted to emergency tracheostomy procedures, typically performed as life-saving measures during acute airway obstruction (1). Attempts at tracheal reconstruction were largely unsuccessful due to the absence of suitable anesthesia, inadequate surgical tools, and the prevailing belief that tracheal cartilage lacked sufficient regenerative. As a result, tracheal resection and reconstruction were long considered unfeasible (2). The modern era of tracheal surgery began to take shape in the mid-20th century. While early attempts at tracheal resection were performed with limited success, it was the pioneering work of Dr. Hermes C. Grillo in the 1960s that truly transformed the field. Through systematic study of tracheal anatomy, vascular supply, and biomechanics, Dr. Grillo developed standardized and safe techniques for segmental tracheal resection followed by primary end-to-end anastomosis. His work demonstrated that segmental resection of the trachea followed by primary end-to-end anastomosis was feasible and safe (3)(4).

Interventions

PROCEDUREcervical collar or cervical-thoracic orthosis.

postoperative cervical spine flexion maintained using non-invasive techniques, such as a cervical collar or cervical-thoracic orthosis.

DEVICEchin-to-chest (Grillo) suturing

cervical spine flexion maintained using traditional chin-to-chest (Grillo) suturing

Sponsors

Sohag University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
6 Months to 80 Years
Healthy volunteers
No

Inclusion criteria

* All pediatric and adult patients undergoing tracheal and cricotracheal resection for benign air way stenosis * All pediatric and adult patients undergoing tracheal and cricotracheal resection for malignant pathologies

Exclusion criteria

* patients with previous cervical spine surgery. * Congenital or acquired spinal deformities.

Design outcomes

Primary

MeasureTime frameDescription
cervical spine flexion2 yearsMaintain Neck Flexion and Reduce Anastomotic Tension After Tracheal Resection

Countries

Egypt

Contacts

Primary ContactAbdelrahman Talal Mahmoud, Assisstent lecturer
abdelrahman_ahmed@med.sohag.edu.eg01001317023
Backup ContactKhaled Mohamed Abdelaal

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026