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Meaning-centered Intervention for Internalizing Symptoms

A Meaning-centered Intervention for Individuals Who Tend to Feel Down or Anxious

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07058181
Enrollment
155
Registered
2025-07-10
Start date
2024-11-28
Completion date
2026-02-23
Last updated
2026-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depressive and/or Anxiety Symptoms

Keywords

meaning-centered intervention, internalizing symptoms, young adults

Brief summary

Young adults with internalizing symptoms will be randomly assigned to a six-session meaning-centered intervention condition or a waitlist condition. Both conditions receive the same questionnaires at baseline, post assessment (intervention condition: immediately after the final session; waitlist: four weeks after baseline), and follow-up. The researchers hypothesize that a meaning-centered intervention for individuals with internalizing symptoms will increase participants' meaning in life and reduce their internalizing symptoms at post assessment and 4-week follow-up when compared to a waitlist condition.

Detailed description

First-year psychology students at the University of Groningen will be screened for depressive and anxiety symptoms. Those with heightened symptoms will be invited via e-mail to participate in the study. After filling out the baseline assessment online, participants will be randomly assigned to either a meaning-centered intervention condition, which will receive a meaning-centered intervention taking place approximately every four days, or a waitlist condition, which will be assigned no task. Participants in the intervention condition will follow six 1-hour online intervention sessions led by a trainer and conduct intervention-related homework assignments. The sessions can be followed in English, Dutch, or German. The intervention aims to increase participants' meaning in life and reduce their internalizing symptoms (i.e. depressive and/or anxiety symptoms). Immediately after the final session (i.e. approximately one month after the baseline assessment), participants in the intervention condition will be asked to fill in the post assessment, which includes the same questionnaires as the baseline assessment. Participants in the waitlist control will be asked to complete the post assessment one month after their baseline assessment. One month after the post assessment, participants in both conditions are asked to fill in same set of questionnaires. Waitlist participants are offered to receive the intervention sessions after the study has finished. Participants are compensated with SONA credits.

Interventions

Meaning-centered intervention for internalizing symptoms adapted from the intervention "Meaning-centered intervention for youth worrying about their weight and shape". * Six 1-hour individual online sessions, approximately every 4 days * Sessions led by a certified trainer based on intervention manual * Four sources of meaning will be explored: personal life story, dealing with life's limitations, creating one's own life, and meaningful experiences * Participants follow intervention using intervention workbook * Homework assignments designed to deepen participants' experience and reflection on meaning in their daily lives

Sponsors

University of Groningen
Lead SponsorOTHER
University of Amsterdam
CollaboratorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* heightened internalizing symptoms (depressive and/or anxiety symptoms) as indicated by PHQ-4 total score of 2 or higher

Exclusion criteria

* receiving psychotherapeutic treatment for a depressive or anxiety disorder * suicidality

Design outcomes

Primary

MeasureTime frameDescription
Meaning in Life Questionnaire; Depression, Anxiety and Stress Scales-21at baseline; post (one month after baseline); one-month follow-up (one month after post)questionnaire (MLQ: sum score (5-35), 7-point Likert scale (1-7), higher scores indicating higher presence of life meaning; DASS-21: sum score (0-33), 4-point Likert scale (0-3), higher scores indicating higher internalizing symptoms)

Secondary

MeasureTime frameDescription
Dyscontrolled drinking; Three-dimensional meaningat baseline; post (one month after baseline); one-month follow-up (one month after post)questionnaire (Dyscontrolled drinking: sum score (3-27), 9-point Likert scale (1-9), higher scores indicating higher dyscontrolled drinking; Three-dimensional meaning: sum score (11-77), 7-Point Likert scale (1-7), higher scores indicating higher life meaning)

Countries

Netherlands

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 5, 2026