Gingival Recession Generalized Moderate, Gingival Recession Localized Moderate, Tooth Sensitivity
Conditions
Keywords
Dental Hypersensitivity, Tooth Sensitivity, Gingival Recession, Dentin Hypersensitivity, Hydroxyapatite, Biomimetic Hydroxyapatite, Toothpaste, Mouthwash, Visual Analogue Scale (VAS), Shiff Air Index, Desensitizing Agents, Oral Health
Brief summary
This randomized controlled clinical trial evaluates the effectiveness of a biomimetic hydroxyapatite-based toothpaste and mouthwash in reducing dental sensitivity in patients with gingival recession. A total of 100 participants will be randomly assigned to two groups. The control group will receive Biorepair Total Protection toothpaste, and the trial group will receive Biorepair high-density mouthwash. Both products will be applied for 30 seconds. Dental sensitivity will be assessed before and after treatment using the Shiff Air Index and the Visual Analogue Scale (VAS).
Interventions
DEVICEBiorepair Total Protection Toothpaste
Application of Biorepair Total Protection toothpaste for 30 seconds, performed once in a clinical setting. The aim is to reduce dental sensitivity in patients with gingival recession.
DEVICEBiorepair High-Density Mouthwash
Application of Biorepair High-Density mouthwash for 30 seconds, performed once in a clinical setting. The aim is to reduce dental sensitivity in patients with gingival recession.
Sponsors
University of Pavia
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Male and female subjects aged between 18 and 70; * Subjects with gingival recession and tooth sensitivity; * Subjects who have agreed to give their free written informed consent to participate in the study.
Exclusion criteria
* Male and female subjects who are not adults; * Subjects without gingival recessions; * Subjects without dental sensitivity; * Subjects with poor participation or insufficient motivation to participate in this study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Dental Sensitivity Measured by the Schiff Air Index | T0 (baseline) and T1 (immediately post-treatment, same visit) | Variation in dental sensitivity scores assessed using the Schiff Air Index at baseline (T0) and after a 30-second application of either toothpaste or mouthwash (T1). The Schiff scale ranges from 0 (no response) to 3 (painful response to air stimulus), with higher scores indicating greater sensitivity. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in Pain Perception Measured by the Visual Analogue Scale (VAS) | T0 (baseline) and T1 (immediately post-treatment, same visit) | Variation in perceived pain intensity related to dental sensitivity, reported by the patient using the Visual Analogue Scale (VAS) at two timepoints: T0 (baseline) and T1 (immediately after 30-second treatment with either toothpaste or mouthwash). The VAS is a 10 cm horizontal line ranging from 0 (no pain) to 10 (worst imaginable pain). |
Countries
Italy
Outcome results
None listed