Nose Diseases
Conditions
Brief summary
this study aims to compare the efficacy of pre-emptive nebulized ketamine versus nebulized dexmedetomidine for post operative pain relief in endoscopic nasal surgery
Interventions
DRUGDexmedetomidine
patients in this group will receive nebulized Dexmedetomidine before onset of surgery
DRUGKetamine
patients in this group will receive nebulized ketamine before onset of surgery
patients in this group will receive nebulized 0.9% normal saline before onset of surgery
Sponsors
Sohag University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* patients between the ages of 20 and 60, * both sexes, * American Society of Anesthesiologists physical status I to II * BMI ≥18≤30 kg/m²
Exclusion criteria
* Patient refusal. * patients with advanced respiratory, renal, hepatic, neurological, or psychiatric disease, pregnant or nursing women. * patients with a history of allergies to any study drugs. * patients who had used central nervous system depressants or analgesics within the previous 24 hours. * patients with hypertension, hypotension, or bradycardia.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| This study aims to assess the efficacy of nebulized dexmedetomidine vs nebulized ketamine to achieve good postoperative pain management in patients undergoing endoscopic nasal surgeries. | 24 hours after operation | post operative pain management by VAS |
Countries
Egypt
Contacts
Primary ContactAhmed T Abdelhameed, Resident
Backup ContactHala M Hashem, Professor
Outcome results
None listed