Laparocele
Conditions
Brief summary
This cross-sectional observational study aims to evaluate the hemodynamic changes induced by different intra-abdominal pressures (IAP) during laparoscopic cholecystectomy under general anesthesia.
Detailed description
Laparoscopic cholecystectomy, a minimally invasive surgery, requires CO₂ insufflation to create a pneumoperitoneum, which alters intra-abdominal pressure and can affect cardiovascular and respiratory stability. This study assesses how varying IAP levels (8-10 mmHg, 12-14 mmHg, and 15-20 mmHg) influence heart rate, blood pressure, oxygen saturation, respiratory rate, and end-tidal CO₂.
Interventions
DIAGNOSTIC_TESTLow Pressure Pneumoperitoneum
Low Pressure Pneumoperitoneum (8-10 mmHg) Details: CO₂ insufflation to 8-10 mmHg IAP, continuous monitoring, measurement at baseline, insufflation, and desufflation.
DIAGNOSTIC_TESTMedium Pressure Pneumoperitoneum
Medium Pressure Pneumoperitoneum (12-14 mmHg) Details: CO₂ insufflation to 12-14 mmHg IAP, parameters measured at key intervals, standard general anesthesia used. High Pressure Pneumoperitoneum (15-20 mmHg) Details: Standard high-pressure technique, monitoring of hemodynamic and respiratory parameters.
Sponsors
Superior University
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* Patients undergoing laparoscopic cholecystectomy under general anesthesia * Age between 18-60 years * ASA physical status I-II * Provided informed consent
Exclusion criteria
* History of cardiovascular or respiratory diseases or other Significant comorbidities affecting hemodynamic stability. * Pregnant patients * Allergies to anesthetic agents
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Self Administered Questioner | 12 Months | Self-Administered Questionnaire for taking different values |
Countries
Pakistan
Outcome results
None listed