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Prevalence of Ascending Aortic Dilation in Sports Medicine

Prevalence of Ascending Aortic Dilation in Sports Medicine

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07050953
Acronym
PRAADS
Enrollment
400
Registered
2025-07-03
Start date
2024-01-01
Completion date
2025-06-01
Last updated
2025-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aortic Aneurysm, Athlete

Brief summary

This study aims to assess the prevalence of ascending aortic dilation in athletes from the general population undergoing routine sports medicine evaluation. It also evaluates the predictive factors and the reproducibility of focused cardiac ultrasound.

Detailed description

Ascending aortic dilation is a potentially serious and underdiagnosed cardiovascular condition, particularly in the context of physical activity. While its prevalence has been studied in elite athletes, little data is available regarding the general athletic population undergoing routine sports medicine evaluation. This study aims to investigate the prevalence of ascending aortic dilation in a general population of recreational and competitive athletes. This is an observational study conducted at the Sports Medicine Department of Caen University Hospital (France). The study will include athletes over the age of 10 who consult for a pre-participation medical evaluation. A focused cardiac ultrasound (FCU) protocol targeting the ascending aorta will be systematically performed using a portable ultrasound device during routine clinical assessment. When indicated, a standard transthoracic echocardiography (TTE) will be used as the reference method for comparison. The primary objective of the study is to estimate the prevalence of ascending aortic dilation in this population. The secondary objective is to explore potential predictive factors, including cardiovascular risk factors and exercise history. This study may help clarify the utility of FCU as a screening tool in sports medicine and contribute to improved early detection of aortic abnormalities in apparently healthy, physically active individuals. Further research may be warranted to assess long-term cardiovascular outcomes in this population.

Interventions

A focused cardiac ultrasound will be performed to measure the dimensions of ascending aorta

Sponsors

University Hospital, Caen
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
10 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Individuals aged 10 years and older * Consulting for a pre-participation sports medicine evaluation at the Caen University Hospital * No known history of cardiovascular disease * Underwent a focused cardiac ultrasound (FCU) of the ascending aorta as part of the consultation * Consent given for use of anonymized medical data for research purposes

Exclusion criteria

* Previous diagnosis of aortic disease or cardiovascular malformation * Incomplete or non-interpretable FCU images * Existing cardiology follow-up with echocardiography less than 3 years old * Refusal to participate or opposition to data use

Design outcomes

Primary

MeasureTime frameDescription
Prevalence of Ascending Aortic Dilation in AthletesBaselineProportion of athletes (recreational and competitive) identified with ascending aortic dilation, as determined by focused cardiac ultrasound. Dilation is defined as an aortic diameter ≥ 40 mm and/or a Z-score ≥ 2, according to age-adjusted reference values.

Secondary

MeasureTime frameDescription
Predictive Factors for Ascending Aortic DilationBaselineAssociation between ascending aortic dilation and clinical variables, including age, sex, blood pressure, body mass index, cardiovascular risk factors, and characteristics of physical activity

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026