Peptic Ulcers
Conditions
Brief summary
Perforation is one of the most severe and life-threatening complications of peptic ulcer disease. This study aims to evaluate the risk factors associated with postoperative morbidity and mortality in patients undergoing surgery for peptic ulcer perforation, with a focus on the timing of presentation, demographic variables, surgical delay, and their association with postoperative outcomes.
Interventions
Emergency laparotomy
Sponsors
Study design
Eligibility
Inclusion criteria
* Patients with peptic ulcer perforation aged\> 15 years and \<75 years. * Patients with duodenal or gastric perforation of peptic ulcer origin. * Patients who underwent simple closure with omental patch as a standard operative procedure.
Exclusion criteria
* Patients treated with conservative management. * Patients with perforation of peptic ulcer origin at the jejunum, ileum adjacent to Meckel's diverticulum. * Patients presenting with recurrent perforation or stomal ulcer perforation.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative Morbidity Rate | 12 months (from patient enrollment to completion of follow-up) | Incidence of postoperative complications (e.g., wound infection, sepsis, anastomotic leak, pneumonia) in patients undergoing surgery for perforated peptic ulcer. |
| Postoperative Mortality Rate | 12 months (from patient enrollment to completion of follow-up) | Incidence of death following surgical intervention for perforated peptic ulcer. |
Countries
Nepal