4 Weeks Supplementation of Huel Ready to Eat Foods
Conditions
Keywords
protein, plant based, Plant protein, inflammation
Brief summary
This project will assess the effect of Huel on markers of gastrointestinal inflammation of 30 generally healthy individuals. The aim is to identify any changes in the markers of inflammation status of volunteers in any of the 9 markers to be monitored. Inflammation status will be measured at the start of the study, after one week of their habitual diets and again after four weeks of consuming two ready to drink Huel products per day, one Hot & Savoury Huel (grain-based option only) and the remainder of their calorie intake to be made up of Huel Powder (v3.1).
Interventions
DIETARY_SUPPLEMENTHuel
Ready to eat huel foods. Containing 2 ready to drink shakes, one savoury meal pack and meal replacement powder. Consumption amounts were based on energy needs of each person
Sponsors
Aelius Biotech
Newcastle University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Masking description
This is an open label study
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
Generally healthy Aged 18 years and over Non-pregnant, Non-lactating non-smoking
Exclusion criteria
Smoker Pregnant Lactating BMI \>30 Food allergy Disordered eating Disorder which could impact the study outcomes Medications which could impact the study outcomes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| C-Reactive protein | baseline and after 4 weeks supplementation |
| neutrophils | baseline and after 4 weeks supplementation |
| TNF-alpha | baseline and after 4 weeks supplementation |
| IL-10 | baseline and after 4 weeks supplementation |
| IL-6 | baseline and after 4 weeks supplementation |
Secondary
| Measure | Time frame |
|---|---|
| Body mass | baseline and after 4 weeks supplementation |
| Body Mass Index | baseline and after 4 weeks supplementation |
| Waist cercumference | baseline and after 4 weeks supplementation |
| linoleic acid | baseline and after 4 weeks supplementation |
| arachidonic acid | baseline and after 4 weeks supplementation |
| alpha-linoleic acid | baseline and after 4 weeks supplementation |
| eicosapentaenoic acid | baseline and after 4 weeks supplementation |
Countries
United Kingdom
Outcome results
None listed