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Post-Operative Analgesic Effect of Tramadol and Nalbuphine in Smoker and Non-Smoker Patients in LC

Post-Operative Analgesic Effect of Tramadol and Nalbuphine in Smoker and Non-Smoker Patients Following Laparoscopic Cholecystectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07049380
Enrollment
132
Registered
2025-07-03
Start date
2025-03-17
Completion date
2026-02-28
Last updated
2025-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparocele

Brief summary

This study aims to compare pain severity and analgesic requirements between smokers and nonsmokers following laparoscopic cholecystectomy, evaluating the efficacy of two analgesics, tramadol and nalbuphine.

Detailed description

The primary objectives are to estimate pain severity in smokers versus nonsmokers and identify the effect of tramadol and nalbuphine between these groups.A comparative cross-Sectional design will be employed from Allama Iqbal Teaching Hospital, DG Khan, over four months. Participants will be stratified into subgroups receiving either tramadol or nalbuphine.

Interventions

DIAGNOSTIC_TESTComparative cross sectional

evaluating the efficacy of two analgesics, tramadol and nalbuphine. The primary objectives are to estimate pain severity in smokers versus nonsmokers and identify the effect of tramadol and nalbuphine between these groups

Sponsors

Superior University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
30 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Both Male and female patients are included. * Adults' patients with Greater than 30 years of age * Both Smoker and non-Smokers patients are added (Patients who are chain smoker at least 10 cigarettes per day).

Exclusion criteria

* Patients are excluded if they have smoking history other than cigarettes smoking like Vapes, Cigar and smokeless tobacco.

Design outcomes

Primary

MeasureTime frameDescription
Visual Analog Scale (VAS)12 MonthsThe Visual Analog Scale (VAS) is a tool used to measure pain intensity, mood, or other subjective experiences. It typically involves a 10 cm (100mm) line with descriptive anchors at each end, such as no pain and worst pain imaginable

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026