Comparison of Conventional and Non-Conventional CRF and Their Association With Acute Coronary Syndrome

Comparison of Conventional and Non-Conventional Cardiovascular Risk Factors and Their Association With Acute Coronary Syndrome

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07049302

Enrollment

222

Registered

2025-07-03

Start date

2025-03-17

Completion date

2026-02-28

Last updated

2025-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Syndrome

Brief summary

This research aims to compare conventional and non-conventional cardiovascular risk factors and their association with Acute Coronary Syndrome (ACS). Conventional risk factors such as hypertension, diabetes mellitus, dyslipidemia, smoking, and family history are well-established contributors to ACS. However, emerging non-conventional risk factors-including elevated inflammatory markers , homocysteine levels, lipoprotein(a), psychological stress, and lifestyle factors-are gaining attention for their potential role in cardiovascular events.

Detailed description

The study will involve a cross-sectional analysis of ACS patients, examining the prevalence and impact of both types of risk factors. By assessing their relative contributions, the study aims to enhance understanding of ACS pathogenesis, identify at-risk populations more accurately, and support more comprehensive prevention strategies. The findings may help broaden clinical risk assessment tools and guide personalized interventions to reduce the incidence of ACS.

Interventions

COMBINATION_PRODUCTConventional Risk Factor Assessment

Participants in Group 1 will undergo evaluation for conventional cardiovascular risk factors associated with Acute Coronary Syndrome (ACS

COMBINATION_PRODUCTNon-Conventional Risk Factor

Participants in Group 2 will be assessed for non-conventional cardiovascular risk factors associated with Acute Coronary Syndrome (ACS).

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adult patients diagnosed with ACS. * Patients providing informed consent for participation.

Exclusion criteria

* Patients with chronic heart diseases unrelated to ACS. * Patients unable to provide consent due to critical illness.

Design outcomes

Primary

Measure	Time frame	Description
Structured Smoking Questionnaire	12 Months	A structured smoking questionnaire is a tool used to assess an individual's smoking habits, level of nicotine dependence, and potential motivations for smoking. These questionnaires typically include questions about cigarette consumption, brand preferences, smoking patterns, and the perceived effects of smoking. nterpretation: Higher scores indicate greater nicotine dependence. Scores: 0-2: Very low dependence 3-4: Low dependence 5: Moderate dependence 6-7: High dependence 8-10: Very high dependence

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026