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Dosimetric Evaluation of Breathing Impact on PTV and Adjacent Organ At Risk in Breast Cancer Radiotherapy

Dosimetric Evaluation of Breathing Impact on Planning Treatment Volumne and Adjacent Organ At Risk in Breast Cancer Radiotherapy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07048639
Enrollment
22
Registered
2025-07-02
Start date
2025-03-17
Completion date
2026-03-01
Last updated
2025-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer

Brief summary

The study is likely an observational study, possibly retrospective or prospective, involving patients with breast cancer undergoing radiotherapy.

Detailed description

Patients with breast cancer scheduled for radiotherapy will be selected based on specific inclusion and exclusion criteria. Patients will undergo imaging studies, such as computed tomography (CT) scans, to define the target volumes and OARs. The study aims to provide insights into the dosimetric impact of breathing motion on PTV and OARs in breast cancer radiotherapy, which can inform strategies to improve treatment planning and delivery.

Interventions

DIAGNOSTIC_TEST4D-CT (Four-Dimensional Computed Tomography)

To assess tumor and organ motion during breathing

Sponsors

Superior University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
25 Years to 40 Years
Healthy volunteers
No

Inclusion criteria

* Patient of breast cancer. * age 25-40

Exclusion criteria

* Patients without breast cancer

Design outcomes

Primary

MeasureTime frameDescription
Physician's Global Assessment (PGA) Scale with scoring details12 MonthsThe Physician's Global Assessment (PGA) scale is a tool used by physicians to evaluate the overall severity of a patient's disease. It's a subjective assessment, typically on a scale of 0 to 3 or 0 to 4, with higher scores indicating more severe disease activity. The PGA focuses on the overall disease activity, considering both the severity of active manifestations and relevant laboratory results, excluding organ damage and subjective findings unrelated to disease activity.

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026