Hyperthyroidism
Conditions
Brief summary
This study is designed to evaluate the thyroid health of healthcare workers exposed to low-dose ionizing radiation at INMOL Cancer Hospital, Lahore. Specifically, it investigates whether prolonged occupational exposure in radiology and nuclear medicine departments is associated with altered thyroid hormone levels or an increased risk of hypothyroidism. The thyroid gland is highly sensitive to radiation, and existing literature suggests a possible link between occupational exposure and thyroid dysfunction.
Detailed description
A cross-sectional research design will be used over a four-month period. A sample of 44 participants will be selected using purposive sampling from the hospital's radiology and nuclear medicine staff.
Interventions
BEHAVIORALThyroid Function Monitoring
This study will include healthcare professionals from the radiology and nuclear medicine departments at INMOL Cancer Hospital with at least one year of radiation exposure. A total of 44 participants will be selected through purposive sampling. Data will be collected using a structured questionnaire and blood tests for thyroid hormones (TSH, T3, T4) to assess thyroid function. Blood analysis will be conducted using CLIA or ELISA methods. The aim is to detect any association between low-dose radiation exposure and thyroid dysfunction.
Sponsors
Superior University
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
20 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* Staff members from radiology and nuclear medicine departments who meet both conditions. * workplace experience exceeding one year * age between 20 to 40 will be selected for this study.
Exclusion criteria
* Employees who have worked less than twelve months * pregnant participants.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| thyroid function assessment | 12 Months | Thyroid function is assessed through blood tests, primarily measuring TSH (Thyroid Stimulating Hormone), T4 (Thyroxine), and sometimes T3 (Triiodothyronine) levels. Abnormal levels of these hormones can indicate an underactive (hypothyroidism) or overactive (hyperthyroidism) thyroid. Normal Ranges (approximate): TSH: 0.4 - 4.0 mIU/L Free T4: 0.7 - 1.9 ng/dL Total T4: 5.0 - 12.0 μg/dL Total T3: 80 - 220 ng/dL |
Countries
Pakistan
Outcome results
None listed