Benign Prostate Obstruction (BPO), Lower Urinary Tract Symptom, Voiding Dysfunction
Conditions
Keywords
Lower Urinary Tract Symptoms, Benign Prostate Obstruction (BPO), Voiding Dysfunction, IPSS, Urolfowmetry
Brief summary
This study aims to identify which symptoms or test findings lead men with lower urinary tract symptoms (LUTS) to consider surgical treatment. Male patients who visit the outpatient clinic for LUTS will be asked whether they would consider surgery in the future if their symptoms persist. Along with this, symptom severity scores (IPSS), quality of life scores, and uroflowmetry measurements such as maximum flow rate (Qmax) and post-void residual volume (PVR) will be collected. The goal is to determine which factors are most strongly associated with a desire for surgery. This is an observational, non-interventional study.
Detailed description
This prospective observational study is designed to evaluate which clinical and uroflowmetry parameters are associated with a desire for surgical treatment in male patients presenting with lower urinary tract symptoms (LUTS). Participants will complete the International Prostate Symptom Score (IPSS) questionnaire, including the quality of life (QoL) item, and undergo uroflowmetry testing. Parameters such as maximum urinary flow rate (Qmax), post-void residual urine volume (PVR), and IPSS subdomain scores (e.g., weak stream, nocturia, urgency) will be analyzed. Patients will also be asked a standardized question regarding their surgical preference if their symptoms remain unchanged. The primary aim is to determine which symptoms or objective findings (e.g., specific IPSS items, reduced Qmax) are most predictive of a preference for surgical intervention. The study will help guide clinical decision-making by identifying symptom patterns or test results that are more likely to prompt patients to consider surgery. No therapeutic intervention will be performed as part of this study.
Interventions
None listed
Sponsors
Marmara University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
MALE
Age
40 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Male patients aged 40 years and older * Presenting with lower urinary tract symptoms (LUTS) * Able to complete the IPSS questionnaire * Undergoing uroflowmetry as part of routine evaluation * Able and willing to provide informed consent
Exclusion criteria
* History of urological surgery (e.g., TURP, HoLEP, radical prostatectomy) * Presence of known prostate or bladder cancer * Active urinary tract infection at the time of evaluation * Neurological conditions affecting voiding (e.g., Parkinson's disease, spinal cord injury) * Inability to perform uroflowmetry or incomplete IPSS data
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Total International Prostate Symptom Score (IPSS) at Baseline | Baseline (at the outpatient clinic visit) | Total IPSS score will be recorded for each participant at the time of initial outpatient clinic evaluation to assess symptom severity. Unit of Measure: Points (0 to 35) |
| Post-Void Residual Urine Volume (PVR) | Baseline (at the outpatient clinic visit) | PVR will be assessed using bladder ultrasound following uroflowmetry at the initial visit. Unit of Measure: Milliliters (mL) |
| Maximum Urinary Flow Rate (Qmax) Measured by Uroflowmetry | Baseline (at the outpatient clinic visit) | Qmax (in mL/sec) will be measured during the initial outpatient visit using non-invasive uroflowmetry. Unit of Measure: Milliliters per second (mL/sec) |
| Patient Preference for Surgery Based on a Standardized Question | Baseline (at the outpatient clinic visit) | Patients will be asked: Would you consider surgical treatment if your symptoms remain unchanged in the future? Response options are Yes/No |
Contacts
Primary Contactgünal özgür, Urology Specialist
Outcome results
None listed