Body Mass Index, Creatine Kinase, Lactate Dehydrogenases, Muscle Damage, Physical Exertion
Conditions
Keywords
drop jump, muscle damage, creatine kinase, lactate dehydrogenase, body mass index, plyometric exercise
Brief summary
This study investigated whether muscle damage induced by a drop jump protocol varies based on participants' body weight and BMI. Fifty healthy adults were divided into normal-weight and overweight groups. All participants completed a standardized drop jump protocol, and blood samples were collected before, immediately after, and 24 hours after exercise. Creatine kinase (CK) and lactate dehydrogenase (LDH) levels were analyzed as biomarkers of muscle damage.
Interventions
BEHAVIORALDrop Jump Protocol
A standardized drop jump (DJ) protocol involving 100 total jumps from a 60 cm platform. Participants performed five sets of 20 jumps, with a 10-second rest between jumps and a 2-minute rest between sets. The protocol was designed to induce muscle damage through eccentric loading.
Sponsors
Melike Nur Eroğlu
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
18 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy adults aged 18-30 * Normal or overweight BMI (18-35 kg/m²) * At least 2 days/week of physical activity * No regular jump training
Exclusion criteria
* Use of medications or supplements * History of musculoskeletal injury * Smoking or alcohol consumption during study period
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Creatine Kinase (CK) Levels | Baseline (pre-exercise), immediately post-exercise, and 24 hours post-exercise | Serum creatine kinase (CK) concentrations measured at three time points: before the exercise protocol, immediately after the protocol, and 24 hours post-exercise. CK is a biomarker of muscle damage. Blood samples were analyzed using a standard biochemical analyzer. |
| Change in Lactate Dehydrogenase (LDH) Levels | Baseline (pre-exercise), immediately post-exercise, and 24 hours post-exercise | Serum lactate dehydrogenase (LDH) concentrations measured at three time points: before the exercise protocol, immediately after the protocol, and 24 hours post-exercise. LDH is used to evaluate exercise-induced muscle damage. Blood samples were centrifuged and analyzed using standardized laboratory techniques. |
Countries
Turkey (Türkiye)
Outcome results
None listed