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TIPS Block vs. IV Analgesia for Postoperative Pain After Knee Arthroscopy

Comparative Study Between Triple Injection Peri-Sartorius (TIPS) Block Versus Intravenous Analgesia for Postoperative Analgesia After Knee Arthroscopy

Status
Not yet recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07046390
Enrollment
52
Registered
2025-07-01
Start date
2025-07-20
Completion date
2026-08-20
Last updated
2025-07-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Arthroscopic Surgery, Nerve Block

Brief summary

In this study participants are aiming to compare triple injection peri-sartorius (TIPS) block versus intravenous analgesia for postoperative analgesia after knee arthroscopy regarding efficacy of pain relief and early ambulation

Detailed description

Arthroscopic knee surgery is a commonly performed orthopedic procedure due to being minimally invasive and providing early recovery. A significant number of patients have severe postoperative pain despite using small incisions leading to poor quality of postoperative recovery. Currently, multimodal analgesia is a widely used method of pain relief and also to improve patient functionality and satisfaction scores. Systemic opioids and non-steroidal anti-inflammatory drugs (NSAIDs) have been the mainstay for treating postoperative pain after knee surgery. The traditional high-dose opioid approach is associated with increased opioid-related side effects eg: (Nausea ,vomiting and delayed recovery ).NSAIDs are effective as part of a multimodal analgesic approach, but their use can be limited due to concerns regarding coagulopathy or impairment of renal function and GIT side effects.Ultrasound guidance in regional anaesthesia is increasingly being used leading to approaches to the sciatic nerve block, femoral nerve block (FNB), adductor canal block (ACB) and obturator nerve block increasingly motivated as an element of multimodal analgesia regimen in many operations, including knee arthroscopy.Sub sartorial block has been studied for its efficacy in providing analgesia following knee surgeries while preserving quadriceps muscle power. However, misnomers have been prescribed at different locations for different block approaches. TIPS block targets motor-sparing analgesia through injection at three planes ultrsound guided.Study Procedures: Patients will be enrolled in this randomly allocated using computer-based randomization into two groups with (26) patients in each group * Group 1 (study group number 1) will receive triple injection peri-sartorius (TIPS) block. The block will be done after induction of general anesthesia before skin incision * Group 2 (study group number 2) (control group )will receive conventional analgesic regimen without having a regional block.

Interventions

DRUGNo intervention

No intervention

Sponsors

Ain Shams University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

.Age 18-40 years undergoing knee arthroscopy. .Sex: Both sexes. .American Society of Anaesthesiologists (ASA) Physical Status Class I and II

Exclusion criteria

.Declining to give written informed consent. .History of allergy to the medications used in the study. .Contraindications to regional anesthesia (including patient refusal, coagulopathy and local infection). Psychiatric disorder. .American Society of Anesthesiologists (ASA) Physical Status Class III and IV. * Patients with body mass index (BMI) \>35 kg/m2 .Neurological deficits or mobility-related disorders of the non-operated limb . * Moderate to severe hepatic , renal diseases and cardiac disease.

Design outcomes

Primary

MeasureTime frame
postoperative analgesics24 hours postoperative

Secondary

MeasureTime frame
The secondary outcomes will be the total morphine consumption in mg , ambulation distances during the first 24 hours postoperative in meters24 hours postoperative

Countries

Egypt

Contacts

Primary Contactabdelrahman mohammed hanafy, master
abdelrhmanhanafy@med.asu.edu.eg01114359788

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026