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Treatment of Overactive Bladder With Anticholinergic Agents

Evaluation of Anticholinergic Treatment Response and Predictive Factors in Pediatric Overactive Bladder

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07046156
Enrollment
120
Registered
2025-07-01
Start date
2022-09-01
Completion date
2026-06-01
Last updated
2025-07-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Overactive Bladder

Keywords

overactive bladder, children, oxybutynin, propiverine, tolterodine

Brief summary

This study aims to evaluate the efficacy and adverse effect incidence of three different anticholinergics (oxybutinin, propiverine, and tolterodine) that are used in children with overactive bladder.

Detailed description

A total of approximately 150 patients with overactive bladder will be evaluated retrospectively. Clinical and demographic data and voiding diaries of these patients will be evaluated. For this purpose, patients will be divided into mainly three groups according to the anticholinergic agent used.

Interventions

Oxybutynin in a dose of 0.5 mg/kg will be used in the treatment of overactive bladder

Propiverine in a dose of 0.8 mg/kg will be used in the treatment of overactive bladder

DRUGTolterodine

Tolterodine in a dose of 0.1 mg/kg will be used in the treatment of overactive bladder

Sponsors

Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
5 Years to 17 Years
Healthy volunteers
No

Inclusion criteria

* Patients diagnosed with overactive bladder * Patients treated with an anticholinergic

Exclusion criteria

* Presence of anatomical or neurological problems * Patients with missing data

Design outcomes

Primary

MeasureTime frame
Number of patients treated with anticholinergic6 months
Number of patients with drug related adverse effects1 month

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026