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The Impact of Untreated Depression and Anxiety Among Patients With Skin Diseases in Jeddah, Saudi Arabia.

The Impact of Untreated Depression and Anxiety in Patients With Skin Diseases: A Cross-sectional Study in Jeddah

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07046039
Enrollment
215
Registered
2025-07-01
Start date
2024-01-01
Completion date
2024-07-29
Last updated
2025-07-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne Vulgaris, Alopecia Areata, Atopic Dermatitis (Eczema), Hidradenitis Suppurativa (HS), Psoriasis, Rosacea, Vitiligo

Keywords

Psychodermatology, Untreated mental health

Brief summary

The goal of this observational study is to learn about the prevalence and severity of untreated depression and anxiety among adults with skin diseases in Jeddah, Saudi Arabia. The main question it aims to answer is: Do patients with skin diseases experience significant levels of untreated depression and anxiety? Participants diagnosed with skin conditions such as acne, eczema, or psoriasis completed the PHQ-9 and GAD-7 questionnaires to assess their mental health symptoms. The study also explores whether factors like age or type of skin disease are associated with more severe psychological distress.

Detailed description

This cross-sectional observational study was conducted to assess the prevalence and severity of untreated depression and anxiety among adult patients diagnosed with common dermatological conditions in Jeddah, Saudi Arabia. The study focused on patients living with acne vulgaris, atopic dermatitis (eczema), psoriasis, vitiligo, rosacea, hidradenitis suppurativa, and alopecia. Conditions that are not only physically distressing but also associated with significant psychological impact. Participants were recruited through dermatology clinics and online platforms. Standardized and validated screening tools, including the Patient Health Questionnaire-9 (PHQ-9) and the Generalized Anxiety Disorder-7 (GAD-7), were used to evaluate symptoms of depression and anxiety. Participants were eligible if they were between 18-65 years old, residing in Jeddah, and had not received prior psychiatric treatment for depression or anxiety. The study also examined potential correlations between psychological distress and clinical or demographic variables such as age, sex, income level, education, and disease severity. Statistical analyses were conducted to identify significant predictors of untreated mental health symptoms in this population. By quantifying the emotional burden associated with skin disease and identifying at-risk subgroups, the study aims to support the integration of routine mental health screening into dermatologic practice. The findings underscore the need for a more comprehensive, biopsychosocial approach to dermatology care in Saudi Arabia, where psychological symptoms are often underrecognized and undertreated.

Interventions

None listed

Sponsors

King Abdulaziz University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Inclusion Criteria: 1. Adults aged 18 to 65 years 2. Residents of Jeddah, Saudi Arabia 3. Diagnosed with one or more of the following skin diseases: acne vulgaris, atopic dermatitis (eczema), psoriasis, vitiligo, rosacea, hidradenitis suppurativa, or alopecia areata 4. Able to complete the study questionnaire in Arabic or English *

Exclusion criteria

1. Age below 18 or above 65 years 2. Absence of diagnosis for the specified skin diseases 3. Presence of chronic systemic illnesses such as diabetes, cardiovascular diseases, hypertension, or epilepsy 4. Inability to provide informed consent or complete the questionnaire

Design outcomes

Primary

MeasureTime frameDescription
Prevalence of untreated anxiety1 day (Assessed at one point in time during the study.)The proportion of patients with dermatological conditions who score above the clinical threshold for anxiety on the Generalized Anxiety Disorder-7 (GAD-7) scale.
Prevalence of untreated depression1 day (Assessed at one point in time during the study.)The proportion of patients with dermatological conditions who score above the clinical threshold for depression on the Patient Health Questionnaire-9 (PHQ-9).

Secondary

MeasureTime frameDescription
Correlation between skin disease severity and psychological distress1 day (Assessed at one point in time during the study.)Statistical assessment of the relationship between the severity of skin diseases (categorized as mild, moderate, or severe) and the levels of depression and anxiety symptoms.

Countries

Saudi Arabia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026