Thyroid Disorder
Conditions
Brief summary
this study aims to compare between effects of lidocaine and ketamine infusion on postoperative analgesia in patients undergoing thyroidectomy.
Interventions
DRUGgroup L : will receive lidocaine
group L : will receive 1.5 mg/kg bolus of iv lidocaine 10 minutes before anaesthesia induction then continuous iv infusion rate 1.5 mg / kg / h
DRUGgroup k : will receive Ketamine
patients will receive .25 mg / kg bolus of iv ketamine 10 minutes before anaesthesia induction then continuous iv infusion of ketamine at .25 mg /kg /h
DRUGgroup c: will recieve .9% saline
group c will be injected with equivalent volumes and rates of .9% saline using the same application scheme as the lidocaine and ketamine as a control group
Sponsors
Sohag University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* age from 18 to 75 years old * both sexes * scheduled for thyroidectomy
Exclusion criteria
* toxic goiter * (BMI) exceeding 30 kg / m2 * un controlled hypertension * sever liver or kidney disorders * allergy to study drugs * hyperthyroidism
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the effect of perioperative intravenous lidocaine and ketamine infusion for postoperative analgesia in patients undergoing thyroidectomy | 24 hours posftoperative | postoperative pain by Numerical Rating Scale (NRS) Zero means no pain and ten means worst pain |
Countries
Egypt
Contacts
Primary ContactMario N Ishak, Resident
Backup ContactAbdel Rahman H Abdel Rahman, Professor
Outcome results
None listed