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Efficacy of Vonoprazan Based Dual and Triple Therapy for Patient With Helicobacter Pylori Infection

Efficacy of Vonoprazan Based Dual and Triple Therapy for Naive Patient With Helicobacter Pylori Infection

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07045688
Enrollment
150
Registered
2025-07-01
Start date
2025-05-13
Completion date
2025-11-25
Last updated
2025-07-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

H. Pylori Infection

Brief summary

This study aims to assess Efficacy of vonoprazan based dual and triple therapy for naïve patient with Helicopacter Pylori infection in Sohag Government .

Interventions

DRUGEfficacy of PPI based triple therapy for naive patient with Helicobacter Pylori infection

we assess the efficacy of PPI based triple therapy for eradication of Helicobacter Pylori infection in naive patient.

DRUGEfficacy of Vonoprazan based dual therapy for naive patient with Helicobacter Pylori infection

we assess the efficacy of Vonoprazan based dual therapy for eradication of Helicobacter Pylori infection in naive patient.

DRUGEfficacy of Vonoprazan based triple therapy for naive patient with Helicobacter Pylori infection

we assess the efficacy of Vonoprazan based triple therapy for eradication of Helicobacter Pylori infection in naive patient.

Sponsors

Sohag University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Age: \>18 years old. * H. pylori infection: Confirmed by histopathology or non-invasive tests (e.g., stool antigen test).

Exclusion criteria

* Prior H. pylori treatment: Previous treatment for H. pylori infection. * Allergies: Known allergies to study medications or components. * Patients cannot finish treatment course. * Patient missed follow up. * Patients refusing or neglecting test of cure for H. pylori.

Design outcomes

Primary

MeasureTime frameDescription
efficacy medical treatment for eradication of Helicobacter Pylori infection in naive patient.4 weeks after successful medical treatmentstool antigen for H. Pylori

Countries

Egypt

Contacts

Primary ContactAndrew K Wadea, Resident
andrewkameel511@gmail.com01211498813
Backup ContactHamdy S Mohammed, Professor
01111101934

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026