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Ultrasonographic Evaluation of the Ulnar Nerve in Individuals With and Without Generalized Joint Hypermobility

Ultrasonographic Evaluation of the Ulnar Nerve in Individuals With and Without Generalized Joint Hypermobility

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07044986
Enrollment
60
Registered
2025-07-01
Start date
2025-07-01
Completion date
2025-08-01
Last updated
2025-07-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypermobility, Joint

Brief summary

This study will include 30 individuals diagnosed with Generalized Joint Hypermobility (GJH) based on the Beighton score and 30 healthy controls without GJH. Participants will undergo Tinel's test and the flexion-compression test. The presence of ulnar nerve-related symptoms such as pain and numbness will be recorded. Ultrasonographic evaluation of the ulnar nerve will be performed at the level of the medial epicondyle, as well as 2 cm proximal and distal to it. Cross-sectional area and diameter of the ulnar nerve will be measured at each site, repeated three times, and the average will be used. Additionally, ulnar nerve mobility during elbow flexion and extension will be assessed. The nerve will be classified as stable if it remains within the cubital tunnel, subluxated if it moves to the level of the epicondyle, and dislocated if it shifts anterior to the medial epicondyle.

Interventions

OTHERno intervention

no intervention

Sponsors

Beylikduzu State Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

* Aged between 18 and 40 years * A Beighton score of 4 or higher (indicative of Generalized Joint Hypermobility) * Willingness to participate in the study

Exclusion criteria

* Being under 18 or over 40 years of age * History of surgery or fracture in the elbow region * Presence of active infection at the measurement site * Presence of congenital anomaly in the upper extremity * History of surgery involving neural structures in the upper extremity * Presence of malignancy * Pregnancy * Presence of cognitive or psychiatric disorders

Design outcomes

Primary

MeasureTime frameDescription
Ulnar nerve cross-sectional area (CSA) at the 2 cm proximal of medial epicondyle0 dayCSA measurement provides insight into nerve thickening, which may indicate entrapment or irritation.
Ulnar nerve cross-sectional area (CSA) at the medial epicondyle0 dayCSA measurement provides insight into nerve thickening, which may indicate entrapment or irritation.
Ulnar nerve cross-sectional area (CSA) at the 2 cm distal of medial epicondyle0 dayCSA measurement provides insight into nerve thickening, which may indicate entrapment or irritation.
Ulnar nerve diameter0 dayUlnar nerve diameter with ultrasonography
Ulnar nerve mobility classification during elbow flexion (stable/subluxated/dislocated)0 dayDynamic USG evaluation allows visualization of nerve movement and instability during joint motion.

Secondary

MeasureTime frameDescription
Presence of ulnar nerve-related symptoms:0 daySymptom inquiry helps correlate clinical complaints with sonographic findings.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026