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Laparoscopic Versus Open Surgical Repair of Genitovesical Fistula in Females

Laparoscopic Versus Open Surgical Repair of Genitovesical Fistula in Females :ِ A Prospective Comparative Non Randomized Study

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07043062
Enrollment
50
Registered
2025-06-29
Start date
2024-08-01
Completion date
2025-08-01
Last updated
2025-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Genitovesical Fistula

Brief summary

Fistula is an abnormal passway that connects two organs or vessels that do not connect normally. Genitourinary fistula refers to a fistula that occurs between reproductive tract organs (vagina, cervix, and uterus), and lower urinary tract (bladder, urethra, and pelvic ureters). It is a serious condition which can significantly influence the biological and psychological condition of women, with a negative impact on the quality of life.

Detailed description

Fistula is an abnormal passway that connects two organs or vessels that do not connect normally. Genitourinary fistula refers to a fistula that occurs between reproductive tract organs (vagina, cervix, and uterus), and lower urinary tract (bladder, urethra, and pelvic ureters). It is a serious condition which can significantly influence the biological and psychological condition of women, with a negative impact on the quality of life. In developed countries, iatrogenic injury during hysterectomy or pelvic surgery is the primary cause of fistulae . However, the etiology differs in developing countries, being secondary to prolonged, obstructed, complicated labor. Genitovesical fistulae are one of the most devastating complications in the urogynecology setting. The commonest type of these fistulae is the vesicovaginal fistula (VVF);the patients Suffering from continuous urinary leakage through the vagina and urinary smell, patients with VVF face hygienic, social, infectious, psychological, and sexual problems. Vesicouterine fistulae (VUF) are not as common as VVF. In 1908, the first case was reported by Knipe , and later in 1957, Youssef reported on the classic symptoms of VUF. These symptoms included amenorrhea and cyclic hematuria, or menouria; known afterward as Youssef's syndrome. The prevalence of these fistulae is estimated to be 1-4% of all genitourinary fistulae. Several options for the management of such fistulae have been discussed; these include conservative treatment with prolonged catheterization , open surgery, cysto-fulguration, endourology, and laparoscopy/robotic surgery. The decision-making is guided by the patient characteristics, etiology, and the experience of the treating surgeon. Laparoscopy is of great advantage when compared to open surgery, including safe, effective, minimally invasive procedure, less postoperative pain, smaller incisions, lower blood loss, a shorter hospital stay, and faster recovery. It is associated with a lower incidence of postoperative complications, including infections and improper wound healing

Interventions

PROCEDUREOpen surgical Interference

to compare the outcomes of Laparoscopic repair versus Open surgical repair of Genitovesical fistula in females.

Sponsors

South Valley University
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Age
25 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

* Females with Vesicovaginal fistula or Vesicouterine fistula. * Timing of repair after 2-6 months of beginning of symptoms and signs of fistula.

Exclusion criteria

* Malignant , Recurrant or Post Radiation Genitovesical fistula. * Females with congenital disease in Bladder ,Uterus or Vagina. * Females with Vaginal or Uterine prolapse.

Design outcomes

Primary

MeasureTime frameDescription
Treatment of Genitourinary fistulaFrom base line to 2 Months from the starting of the operationTo examine the female patients whom suffering fromGenitourinary fistula, either by surgical interference or Laparoscopy

Countries

Egypt

Contacts

Primary ContactHassan Elshazly Khodary Hassanein, MSC
hassanelshazly67@gmail.com+201006769357
Backup ContactAhmed Mahmoud Hassan, Assist.prof
drahmeduro20060@gmail.com+201069611961

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026