Effects of Pulmonary Resection on Right Ventricular Function

Echocardiographic Assessment of Right Ventricular Function After Pulmonary Resection

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07042893

Enrollment

Registered

2025-06-29

Start date

2025-04-01

Completion date

2026-05-15

Last updated

2026-08-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiothoracic Anesthesia, Echocardiography, Pulmonary Resection, Right Ventricular Function

Keywords

pulmonary resection, right ventricular function, echocardiography, cardiothoracic anesthesia

Brief summary

Lung resection is associated with high postoperative morbidity and mortality and leads to a significant long-term decrease in functional capacity, particularly due to cardiorespiratory complications. One of the contributing factors to this functional decline is the postoperative reduction in right ventricular function. Due to the anatomical proximity and interactions, right ventricular function is evaluated by echocardiography following lung resection. The pulmonary artery pressure (PAP)/tricuspid annular plane systolic excursion (TAPSE) ratio is a parameter that provides a more comprehensive assessment of right heart function by evaluating both right ventricular systolic function and pulmonary artery pressure. In this study, investigators aimed to evaluate changes in right heart function by performing preoperative and postoperative echocardiographic assessments in participants undergoing lung resection, focusing on PAP/TAPSE ratios.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

Adults aged 18 to 80 years ASA classification I-III Patients scheduled to undergo lung resection in thoracic surgery

Exclusion criteria

Patients with arrhythmia Patients using antiarrhythmic drugs Patients with renal failure requiring hemodialysis Patients with a history of previous lung surgery Patients with valvular heart disease Patients with a history of angina pectoris or myocardial infarction within the past month Patients with FEV1/FVC ratio below 60%

Design outcomes

Primary

Measure	Time frame	Description
Echocardiographic Assessment: TAPSE/PASP Ratio	Preoperatively, on postoperative days 2-4, and at postoperative month 2	Patients will undergo transthoracic echocardiographic evaluation preoperatively, on postoperative days 2-4, and at postoperative month 2. The TAPSE/PASP ratio will be calculated and recorded in mm/mmHg as a non-invasive surrogate of right ventricular-pulmonary arterial coupling.
Echocardiographic Assessment: Tricuspid Annular Plane Systolic Excursion (TAPSE)	Preoperatively, on postoperative days 2-4, and at postoperative month 2	Patients will undergo transthoracic echocardiographic evaluation preoperatively, on postoperative days 2-4, and at postoperative month 2. TAPSE will be measured and recorded in millimeters (mm).

Countries

Turkey (Türkiye)

Outcome results