Geriatrics Rehabilitation
Conditions
Brief summary
Subject with sarcopenia get modified poco-poco exercise program for 12 weeks
Detailed description
34 participants (\>60 years) with sarcopenia were modified poco-poco exercises three times weekly for 12 weeks will assessed sarcopenia staging (determined by assessing skeletal muscle index, muscle strength, physical performance) and levels of global DNA methylation and GDF-15.
Interventions
PROCEDUREModified poco-poco exercises
Participants performed modified poco-poco exercises three times weekly for 12 weeks
Sponsors
Universitas Padjadjaran
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
All research subjects received modified poco-poco exercise program for 12 weeks
Eligibility
Sex/Gender
ALL
Age
60 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age above 60 years old * Have sarcopenia (based on AWGSOP 2019 criteria)
Exclusion criteria
* Hearing impairment/loss hindering participants to receive verbal instructions * Vision impairment/loss hindering participants to receive instructions * Musculoskeletal impairment or severe joint diseases (i.e. deformity in Osteoarthritis or Rheumatoid Arthritis) * Participants have been involved in other exercise program * Severe cardiovascular disease diagnosed by Cardiologist. * Participants will be excluded from the research if they skip 3 sessions of the program consecutively or skip 5 sessions cumulatively
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Sarcopenia Staging (Skeletal Muscle Index) | 12 weeks | Skeletal muscle index |
| Sarcopenia Staging (Muscle Strength) | 12 weeks | Hand Grip Strength, score in kilograms |
| Sarcopenia Staging (Physical Performance) | 12 weeks | Short Physical Performance Battery, score in numerical 0-12 |
| Levels of Global DNA Methylation | 12 weeks | Global DNA methylation levels were analyzed using the ELISA-based kit |
| Levels of Growth Differentiation Factor 15 | 12 weeks | Growth Differentiation Factor 15 were analyzed the Quantikine ELISA Human GDF-15 Immunoassay |
Countries
Indonesia
Outcome results
None listed