Cerebral Infarction
Conditions
Keywords
cerebral infarction
Brief summary
The goal of this clinical trial is to learn if the application of fluorodeoxyglucose positron emission tomography can predict prognosis of stroke patients. The main questions it aims to answer are: * Does FDG PET can predict future vascular events such as stroke recurrence, myocardial infarction or vascular death among stroke survivors? * Does FDG PET can predict other important events such as fracture, dementia, bleeding, cancer and overall death among stroke survivors? Researchers will compare the FDG uptake in major organs - such as the amygdala, vertebrae, spleen, liver, internal carotid artery, visceral fat, and psoas muscle - between patients with and without the event of interest to determine whether FDG PET can predict the overall prognosis of stroke patients. Participants will: * Undergo whole-body FDG PET once their neurological status has stabilized after stroke. * Complete questionnaires assessing stress and anxiety (PHQ-9 and PSS-10) on the same day. * Maintain regular clinic visits for up to 24 months following the index stroke
Interventions
DIAGNOSTIC_TESTFDG-PET
The participants undergo whole-body FDG PET once their neurological status has stabilized after stroke.
Sponsors
Seoul National University Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* acute ischemic stroke patients who admitted within seven days after symptom onset
Exclusion criteria
* Patients with unstable vital signs or neurological symptoms * Patients with estimated glomerular filtration rate less than 30ml/min * Patients with uncontrolled diabetes requiring persistent insulin injection * During pregnancy or while breastfeeding * Patients with impaired consent capacity * Patients with diagnosed/treatment for dementia * Patients undergoing treatment for malignant tumors or serious autoimmune diseases
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Vascular events | up to 24 months after index stroke | Stroke, myocardial infarction, vascular death |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| overall vascular events | up to 24 months after index stroke | primary vascular events plus transient ischemic attack, venous thromboembolism, peripheral artery disease requiring intervention or hospitalization |
Other
| Measure | Time frame | Description |
|---|---|---|
| Overall events | up to 24 months after index stroke | fracture, cancer, bleeding, dementia, overall death |
Countries
South Korea
Outcome results
None listed