Hemodynamics, Low-flow Anesthesia, Open-heart Surgery
Conditions
Keywords
Low-flow anesthesia, Hemodynamics, Open-heart surgery
Brief summary
Low-flow anesthesia (LFA) is a technique in which at least 50% of the exhaled air, after carbon dioxide absorption, is mixed with a certain amount of fresh gas and returned to the patient during the next inspiration. In 1974, R. Virtue defined minimal flow anesthesia (MFA) as 0.5 L/min. In 1984, Baker and Simionescu classified LFA as 0.5-1 L/min and MFA as 0.25-0.5 L/min. The aim of this study is to investigate whether there are hemodynamic differences between open-heart surgery cases performed with LFA at different fresh gas flow rates.
Interventions
None listed
Sponsors
Çağrı Özdemir
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
-≥18 years and scheduled for open-heart surgery patients -ASA I-II-III-IV physical class
Exclusion criteria
* Emergency cases * Patients under 18 years of age * Patients who have had open heart surgery before * Patients for whom the use of inhaled anesthetic agents is contraindicated * Patients who do not sign a voluntary consent form
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| physiological parameter ; heart rate | Intraoperatively | Heart rate will be recorded every 10 minutes, expressed as beats per minute, starting before induction and including the sternotomy and pericardiotomy periods. |
| physiological parameter; systolic/diastolic blood pressure | Intraoperatively | Systolic and diastolic blood pressure will be recorded every 10 minutes in mmHg, starting before induction and including the sternotomy and pericardiotomy periods. |
| physiological parameter; SpO2 | Intraoperatively | SpO2 will be recorded as a percentage every 10 minutes, starting before induction and including the sternotomy and pericardiotomy periods. |
| Monitoring parameter; Bispectral Index (BIS) | Intraoperatively | The BIS value will be recorded numerically every 10 minutes, starting from before induction and including the sternotomy and pericardiotomy periods. |
| Monitoring parameter; Minimum alveolar concentration (MAC) | Intraoperatively | The MAC value will be recorded numerically every 10 minutes, starting from before induction and including the sternotomy and pericardiotomy periods. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Preoperative data; ASA (American Society of Anesthesiologists) classification | 24 hours before surgery | During the preoperative period, preoperative data, including the American Society of Anesthesiologists (ASA) Physical Status Classification, will be recorded. The ASA classification is used to assess the patient's preoperative physical status and perioperative risk, with higher ASA classes (I-IV) indicating increased systemic disease severity and perioperative risk. |
| Preoperative data | 24 hours before surgery | In the preoperative period, the degree of valve dysfunction (such as I.degree TY, II.degree MY) of the patients will be recorded. |
| Preoperaitive data | 24 hours before surgery | In the preoperative period, the patient's ejection fraction will be recorded as a percentage. |
Countries
Turkey (Türkiye)
Contacts
CONTACTÇağrı Özdemir
Outcome results
None listed