Acute Kidney Injury, Preeclampsia
Conditions
Keywords
preeclampsia, VEXUS score, AKI
Brief summary
To evaluate diagnostic accuracy of venous excess ultrasound score to predict acute kidney injury
Detailed description
Preeclampsia is a common health problem during pregnancy. such condition may result in serious consequences including acute kidney injury. researchers of this study aim to evaluate the ability of venous excess ultrasound score at hospital admission to predict acute kidney injury in preeclampsia with severe features
Interventions
DEVICEVenous excess ultrasound score (VEXUS)
Doppler examination of inferior vena cave, portal vein, hepatic vein, and intrarenal vein will be conducted by an experienced operator
Sponsors
Cairo University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* preeclampsia with severe features
Exclusion criteria
* Patient refusal * Preexisting renal impairment (defined as baseline serum creatinine \> 1.3 mg/dl) * Inability to obtain adequate Doppler views * Renal transplantation * Previous need for renal replacement therapy * Known peripheral vascular disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The accuracy of VEXUS score at admission to predict acute kidney injury | within 48 hours of admission |
Secondary
| Measure | Time frame |
|---|---|
| need for renal replacement therapy | at 28 days of admission |
| Cumulative fluid balance | within 48 hours of admission |
| In hospital mortality | At 28 days of admission |
Countries
Egypt
Outcome results
None listed