Immune-Nutritional Indexes (PNI, HALP), Postoperative Sleep Quality
Conditions
Brief summary
This prospective observational study aims to evaluate the relationship between preoperative immune-nutritional status and postoperative sleep quality in women undergoing total abdominal hysterectomy under general anesthesia. Immune-nutritional scores, including the Prognostic Nutritional Index (PNI) and Hemoglobin-Albumin-Lymphocyte-Platelet (HALP) score, will be calculated using routine preoperative blood parameters. Postoperative sleep quality will be assessed using the Richards-Campbell Sleep Questionnaire (RCSQ). Secondary outcomes include postoperative pain scores and patient satisfaction. The study will enroll 60 patients and seeks to determine whether preoperative physiological markers can predict subjective recovery parameters such as sleep and comfort, potentially contributing to personalized perioperative care.
Interventions
OTHERImmune-Nutritional Scoring and Postoperative Sleep Assessment
Routine preoperative laboratory data (hemoglobin, albumin, lymphocyte, platelet) will be used to calculate immune-nutritional scores (HALP, PNI). Postoperative sleep quality will be assessed with the Richards-Campbell Sleep Questionnaire (RCSQ).
Sponsors
Istinye University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Female patients aged 18-70 * ASA physical status I-III * Undergoing elective total abdominal hysterectomy under general anesthesia * Available complete blood count and biochemistry results within 24 hours preoperatively * Planned to stay at least one night postoperatively * Sufficient cognitive ability to understand and complete questionnaires * Provided written informed consent
Exclusion criteria
* History of neurological or psychiatric illness * Diagnosed sleep disorders * Current use of sedative or hypnotic medications * Undergoing additional surgical procedures during operation * Requiring postoperative intensive care * Operated under spinal or epidural anesthesia
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative Sleep Quality Score | Postoperative first night | Sleep quality will be measured using the Richards-Campbell Sleep Questionnaire (RCSQ), a validated 5-item instrument assessing sleep depth, latency, number of awakenings, efficiency, and overall quality. Each item is scored from 0 to 100, with higher scores indicating better sleep quality. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative Pain Score | Post-anesthesia care unit (PACU), postoperative day 1 and day 2 (rest and mobilization) | Pain levels will be assessed using the Visual Analog Scale (VAS), ranging from 0 (no pain) to 10 (worst pain imaginable). Scores will be recorded at rest and during mobilization on each postoperative day. |
| Patient Satisfaction Score | Postoperative day 2 | Overall patient satisfaction with the perioperative experience will be assessed using a 0-10 numeric rating scale, with higher scores indicating greater satisfaction. |
Contacts
Primary Contactilke dolgun
Outcome results
None listed