Chronic Limb Threatening Ischemia, Peripheral Arterial Disease, Sarcopenia
Conditions
Brief summary
To evaluate the correlation of Sarcopenia Parameters and Peripheral Artery Disease with chronic limb threatening ischaemia.
Detailed description
Prior researches indicated a relatively high prevalence of sarcopenia among patients of Peripheral Artery Disease. However, the relationship between sarcopenia and progression of Peripheral Artery Disease with chronic limb threatening ischaemia remained poorly understood. Thus, this cohort study aimed to evaluate the correlation of Sarcopenia Parameters, such as psoas muscle area (PMA) and total abdominal muscle area (TAMA) at the L3 vertebral level, measured by computed tomography (CT), and progression of Peripheral Artery Disease with chronic limb threatening ischaemia.
Interventions
OTHERNot applicable- observational study
non-applicable
Sponsors
Fudan University
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Patients of Peripheral Artery Disease, including intermittent claudication and Chronic Limb Threatening Ischemia; * Patients with Rutherford grade 2-6 between Jan.1 2023 and Dec.31 2024; * Patients at age 18-80; * Patients underwent an in-hospital routine enhanced whole abdomen to lower extremities CT scan; * Patients able to complete the clinical follow-up for 3 months.
Exclusion criteria
* Poor CT quality or incomplete images; * Incomplete clinical data; * In-hospital mortality during Jan.1 2023 and Dec.31 2024.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| psoas muscle area (PMA) [measured by computed tomography (CT)] | 2023.1.1～2024.12.31 | psoas muscle area (PMA) (square centimeters) was regarded as a kind of typical sarcopenia parameters, measured by computed tomography (CT) at the L3 vertebral level |
| total abdominal muscle area (TAMA) measured by computed tomography (CT) | 2023.1.1～2024.12.31 | total abdominal muscle area (TAMA) (square centimeters) was regarded as a kind of typical sarcopenia parameters, measured by computed tomography (CT) at the L3 vertebral level |
Countries
China
Outcome results
None listed