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Prediction of Postoperative Outcomes After Rectal Resection by the Comprehensive Complication Index (CCI)

Prediction of Postoperative Outcomes After Rectal Resection by the Comprehensive Complication Index (CCI): A Retrospective Comparative Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07037693
Enrollment
958
Registered
2025-06-25
Start date
2012-01-01
Completion date
2024-11-30
Last updated
2025-06-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rectal Diseases

Brief summary

Postoperative complications after rectal resection can worsen the short-term postoperative outcomes and the long-term survival. This study aims to compare the comprehensive complication index (CCI) and the commonly used Clavien-Dindo classification (CDC) in predicting postoperative outcomes after rectal resection.

Interventions

DIAGNOSTIC_TESTComprehensive complication index (CCI)

Comprehensive complication index (CCI)

DIAGNOSTIC_TESTClavien-Dindo-Classification (CDC)

Clavien-Dindo-Classification (CDC)

Sponsors

Cantonal Hospital of St. Gallen
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* All patients with rectal resection at the Cantonal Hospital of St.Gallen between 2012 and June 2024.

Exclusion criteria

* Missing CCI data * Missing CDC data * Incomplete 30-day follow-up * Decline to have their information included in the scientific data analysis * Age under 18 years

Design outcomes

Primary

MeasureTime frameDescription
Length of hospital stayPeriproceduralThe predictive ability of the comprehensive-complication index and the Clavien-Dindo classification regarding the length of hospital stay after rectal resection will be compared through an area under the curve (AUC) analysis.

Secondary

MeasureTime frameDescription
30-day readmission rate30 daysThe predictive ability of the comprehensive-complication index and the Clavien-Dindo classification regarding the 30-day readmission rate after rectal resection will be compared through an area under the curve (AUC) analysis.
90-day mortality90 daysThe predictive ability of the comprehensive-complication index and the Clavien-Dindo classification regarding the 90-day mortality after rectal resection will be compared through an area under the curve (AUC) analysis.
Overall survival5 yearsThe patients 5-year overall survival will be compared between patients with low comprehensive-complication index and high comprehensive-complication index. A high comprehensive-complication score was defined as a score above the median score of the patients with a Clavien-Dinco classification grad 3a complication.
Comprehensive measure30 daysEvaluation of the comprehensive measure of the comprehensive-complications index through analysis of the number and severity of all complications for patients with multiple complications. Comparison of the range of the comprehensice complications-index score in patients with the same Clavien-Dindo classification.

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026