Cardiac Resynchronization Therapy
Conditions
Keywords
inspiratory muscle training, cardiac resynchronization therapy, exercises capacity, quality of life
Brief summary
Patients who are followed up in the cardiology clinic with a diagnosis of CHF, who have had a CRT implant at least 1 year ago, and who do not receive cardiac rehabilitation will be included. The aim of the study is to investigate the effects of inspiratory muscle training (IMT) on exercise capacity, respiratory muscle strength, NTproBNP and quality of life. Groups Intervention group: Treatment with IMT Control group: Standard care Study hypothesis; 1. Does IMT have an effect on exercise capacity and quality of life in patients with CRT? 2. Does IMT have an effect on NTproBNP in patients with CRT?
Interventions
OTHERinspiratory muscle training
inspiratory muscle traning MIP%40-60
OTHERstandart care
standart care
Sponsors
Tarsus University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Masking description
Doctor who doing ekogardiography.
Eligibility
Sex/Gender
ALL
Age
45 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Patients who were followed up in the cardiology clinic with a diagnosis of CHF, * CRT implanted at least 1 year ago, * did not receive cardiac rehabilitation, * 45-75 years old, * communicate in Turkish, * NYHA II-III
Exclusion criteria
* orthopedic and neurological disorders that may prevent walking, * acute respiratory tract infection in the last month, * NYHA I were not included in this study because they were generally not hospitalised and the problems were managed with outpatient diagnosis and treatment, and patients with class IV were not included in this study because they showed severe symptoms for medical and ethical reasons and they were not wanted to be forced with this long-lasting survey application process.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| NT-proBNP | enrollment and end of the 12 week treatment | NT-proBNP |
| Exercises capacity | enrollment and end of the first week of treatment | Exercise capacity was evaluated using the 6-minute walk test (6MWT). 6MWT was performed according to the ATS/ERS criteria. |
| Heart rate (Exercises capacity) | enrollment and end of the first week of treatment | Heart rate were measured using a portable pulse oximeter (Cosmed Srl, Cosmed Spiropalm, Rome, Italy), before, after and 1 minute recovery. |
| Quality of Life of patients | enrollment and end of the 12 week treatment | Qality of life was assessed using the Nottingham Health Profile (NHP) self-reported tool. The NHP questionnaire evaluates six dimensions of health (pain, energy level, sleep, physical abilities, emotional reaction and social isolation) and includes 38 items. Total NHP score ranges between 0-600 and quality of life perception is negatively associated with score received |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Respiratory muscle strength | enrollment and end of the first week of treatment | Respiratory muscle strength was measured with a portable, electronic mouth pressure measuring device (Micro Medical Micro RPM, Rochester, UK). Three measurements were made to obtain the best value. There should not be more than a 10% difference between the two best-measured values. Actual MIP values and percentages of expected values according to age and gender were used in the analysis |
| The performance of patients' activities of daily living | at enrollment and end of the 12 week treatment | The performance of patients' activities of daily living was assessed with the Performance Measurement of Activities of Daily Living Questionnaire-8 (PMDL-8), the Turkish validity and reliability of which was performed by Ertürk et al. The PMADL-8 questionnaire for Patients with Congestive Heart Failure assesses functional limitations in CHF patients based on the ICF model. High scores indicate severe functional limitations. |
Countries
Turkey (Türkiye)
Outcome results
None listed