Caregiver Burden, Ovarian Cancer, Patient Burden
Conditions
Brief summary
Filling the gap in Canadian evidence on the burden of PROC on QoL is essential. It will help better understand the impact of PROC on multiple aspects of the lives of patients and their caregivers and the real-life hurdles faced by PROC patients and their caregivers. The outputs of this study will help better understand the hurdles and challenges they face and the significant unmet medical need.
Interventions
OTHERNo intervention
No specific intervention is assess in this study.
Sponsors
PeriPharm
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
Patient Inclusion Criteria 1. ≥18 years old 2. Patients with PROC who received \>1 prior line of therapy identified through a screening survey. PROC will be defined as recurrence less than 6 months after last platinum chemotherapy (i.e. carboplatin or cisplatin) 3. Ability to read and understand French or English 4. Signature of ICF Patients
Exclusion criteria
1. Patients with PSOC, defined as those who: 1. Have not progressed within less than 6 months after completion of platinum-based chemotherapy or; 2. Are still on platinum chemotherapy or; 3. Receive maintenance therapy. 2. Patients with platinum-refractory ovarian cancer, defined as not responding or disease progressing during therapy or within three months after the last dose Caregivers Inclusion Criteria: 1. ≥18 years old 2. Current caregiver of a patient with PROC (see definition to be used above) who received \>1 prior line of therapy identified through a screening survey. 3. Ability to read and understand French or English 4. Signature of ICF. Caregivers
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| To estimate the quality of life of patient with ovarian cancer | At recruitment | Using the the Functional Assessment of Cancer Therapy - Ovarian (FACT-O) and EuroQol 5-dimendion 5-level (EQ-5D-5L) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Patient's symptoms assessment | At recruitment | Using the Measure of Ovarian Symptoms and Treatment (MOST-T24 (V2)) |
| Caregiver's Quality of Life | At recruitment | Using the CareGiver Oncology Quality of Life (CarGOQoL) questionnaire |
| Patients and caregivers work productivity loss and activity impairment | At recruitment | Using the Work Productivity and Activity Impairment (WPAI) questionnaire |
| Patient's preference in treatment | At recruitment | Using a questionnaire specifically developed for this study based on a literature search, physician input and patient association input. |
Countries
Canada
Outcome results
None listed