Critical Illness, Heart Failure, LVAD
Conditions
Brief summary
All patients undergoing an implantation of a durable left ventricular assist device and monitored by pulmonary artery catheter showing no adverse events after surgery are included in the study and ventilated for 15 minutes using extra thoracic negative pressure ventilation and usual intrathoracic positive pressure ventilation. Hemodynamics changes between both ventilation modes, especially focussing on right ventricular function and measured by a pulmonary artery catheter, are compared.
Interventions
All participants are ventilated with negative pressure ventilation first
All participants are ventilated using positive pressure ventilation after negative pressure ventilation
Sponsors
Karlsburg Hospital
University Hospital Freiburg
Study design
Allocation
NA
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* All patients after implantation of a durable left ventricular assist device
Exclusion criteria
* Complication during surgery like bleeding, emergency, inability to fit the cuirass, unavailability of an investigator, unstable condition regarding circulation or ventilation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| RVSWI | one minute | right ventricular stroke work index |
Countries
Germany
Contacts
CONTACTMatthias Heringlake, Prof. Dr. med.
Outcome results
None listed