Carotid Artery Stenosis, Cerebrovascular Disorders, Coronary Artery Disease
Conditions
Keywords
Coronary Artery Disease, Carotid Artery Stenosis, Doppler Ultrasound, Combined Vascular Intervention
Brief summary
This prospective observational cohort study aims to investigate the prevalence and clinical significance of head and neck arterial stenosis in patients with coronary artery disease (CAD) undergoing or scheduled for percutaneous coronary intervention (PCI). Using Doppler ultrasound as the primary screening tool, the study will assess the degree of stenosis and evaluate the impact of different combined treatment strategies on patient outcomes. The research will provide real-world evidence to optimize integrated care approaches for patients with comorbid cardiovascular and cerebrovascular diseases.
Interventions
PROCEDUREPercutaneous Coronary Intervention
Coronary stenting performed as part of routine care for patients with coronary artery stenosis.
PROCEDURECerebrovascular Intervention (CAS ）
Patients with intervention-indicated head and neck artery stenosis will receive carotid artery stenting based on clinical evaluation.
OTHERNo Intervention / Observation
Clinical observation or standard follow-up in patients without significant disease
Sponsors
Beijing Anzhen Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Age ≥18 years; 2. Patients with coronary artery disease scheduled to undergo elective percutaneous coronary intervention (PCI) on the following day.
Exclusion criteria
1. The expected survival is less than 1 years; 2. Simultaneously merge other serious diseases;
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Prevalence of Head and Neck Artery Stenosis in Patients with Coronary Artery Disease | At baseline (prior to or during initial hospitalization) | The proportion of patients with coronary artery disease who are found to have head and neck artery (e.g., carotid or vertebral artery) stenosis, as determined by duplex ultrasound or other imaging modalities. |
Secondary
| Measure | Time frame |
|---|---|
| mRS score | 7±1 days or the day discharged |
| mRS Score | 90±7 days |
| Rate of cardiovascular and cerebrovascular events | 90±7 days |
| Short-term complications | 90±7 days |
| Long-term complications | 365±30 days |
Countries
China
Contacts
Primary ContactXiaochuan Huo, M.D.
Backup ContactXin Tong, M.D.
Outcome results
None listed