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RaDIANT Health Systems Intervention

The RaDIANT Health Systems Intervention for Improving Access to Kidney Transplantation

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07033117
Enrollment
14000
Registered
2025-06-24
Start date
2025-10-27
Completion date
2027-07-31
Last updated
2026-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End Stage Renal Disease (ESRD), Kidney Disease

Brief summary

The overarching goal of the proposed study is to determine whether the addition of structural interventions at the health system level targeting upstream barriers in the transplant process will improve access to transplant evaluation start.

Interventions

OTHERPerformance Feedback Reports on Referral and Evaluation Closures

Performance feedback reports will reflect each transplant center's performance related to kidney transplant evaluation initiation and referral closure. These reports aim to help centers understand common reasons why patients do not initiate the evaluation process or failed to proceed beyond the evaluation process, and to identify patterns in referral and evaluation closure practices. Reports will be individualized and distributed quarterly to the transplant center champion by the intervention lead.

OTHERDialysis Facility Awareness Campaign

As part of the intervention, dialysis centers will participate in an Awareness Campaign designed to educate staff about transplant center quality improvement efforts and how they may be contacted as part of the project. This campaign may include brief webinars or informative documents distributed via platforms such as IPRO Learn.

OTHERPatient Contact via Preferred Method

Transplant centers will contact patients using their preferred method of communication.

OTHERPhone Call to Dialysis Facility During the Patient's Dialysis Session

Facilities will enhance their patient communication procedures by making a phone call to the dialysis facility during the patient's dialysis session if the patient has not responded to initial outreach attempts. This additional step increases the likelihood of reaching the patient during a time when they are accessible and can engage in scheduling or follow-up.

OTHERPhone Call to Provider

Transplant centers will enhance their outreach procedures by making a phone call to the referring provider (e.g., nephrologist, medical assistant) or another provider involved in the patient's care (e.g., primary care provider) in the event of self-referral if the patient has not responded to initial outreach attempts or "no-shows" an initial evaluation appointment. This additional step ensures that the referring provider is informed of the patient's progress and can assist in re-engagement or decision-making prior to referral closure.

OTHERTransplant Referral Communication Platforms or Email to Communicate Patient Status and No-Show

Transplant center staff will utilize transplant referral communication platforms and/or email to communicate updates to dialysis staff regarding patient status (e.g., unable to contact the patient or no-show) before referral closure.

OTHERAudit and Tracking of Patient Contact Attempts Prior to Referral Closure

Transplant center staff will continue internally tracking the frequency that a patient is contacted before closure and the date of closure, in alignment with center standard practice. This intervention introduces an audit process to be conducted before closure to ensure that all contact attempts (including one or more attempts to contact the patient directly, one or more phone calls to the alternate preferred contact, or one or more attempted contacts to the dialysis unit to connect with the patient), in alignment with center communication procedures, are appropriately executed.

Sponsors

Indiana University
Lead SponsorOTHER
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
CollaboratorNIH
Indiana University Health
CollaboratorOTHER
Emory Healthcare
CollaboratorOTHER
Piedmont Healthcare
CollaboratorOTHER
Medical University of South Carolina
CollaboratorOTHER
Duke University
CollaboratorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes

Inclusion criteria

* Five large transplant centers (Emory Transplant Center and Piedmont Transplant Center in Atlanta, GA; Medical University of SC; Duke University in Durham, NC; and Indiana University in Indianapolis, IN) \~800 referring dialysis center referring to these transplant centers

Exclusion criteria

* Individuals referred, initiating evaluation, and waitlisted at non-participating start centers

Design outcomes

Primary

MeasureTime frameDescription
Change in transplant evaluation start within 6 months of transplant referralBaseline, Post Intervention (Up to one year)The difference in the proportion of patients starting transplant evaluation within 6 months of being referred from baseline to up to one-year post-intervention

Secondary

MeasureTime frameDescription
Change in transplant waitlistingBaseline, Post Intervention (Up to one year)The difference in the proportion of patients waitlisted from baseline and up to one-year post-intervention
Change in transplant receipt among those who were waitlistedBaseline, Post Intervention (Up to one year)The difference in the proportion of patients who received a transplant among those who were waitlisted from baseline and up to one-year post-intervention

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 27, 2026