Neuromuscular Effects of Spinal Manipulation in Individuals Following Anterior Cruciate Ligament Reconstruction

Neuromuscular Effects of Spinal Manipulation in Individuals Following Anterior Cruciate Ligament Reconstruction: A Single-Blinded Randomized Controlled Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07032623

Enrollment

Registered

2025-06-24

Start date

2025-03-03

Completion date

2025-06-03

Last updated

2025-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anterior Cruciate Ligament Reconstruction

Keywords

Knee, Anterior cruciate ligament, Motor control, Electromyography, Physiotherapy

Brief summary

This single-blind, randomized controlled trial aims to investigate the effects of spinal manipulation on neuromuscular control in individuals with anterior cruciate ligament reconstruction during a single-leg vertical drop landing task. The intervention group will receive spinal manipulation, while the control group will not receive any therapeutic intervention. The main question it aims to answer is: • Can spinal manipulation induce changes in muscle activation, co-contraction magnitude, and biomechanical parameters during landing?

Interventions

PROCEDURESpinal Manipulation

The spinal manipulation will target the sacroiliac joint using the global pelvic manipulation technique. Participants will be positioned in lateral decubitus with the ACL-reconstructed limb placed uppermost. The therapist will apply progressive rotation and flexion at the hip and knee joints to increase tissue tension. To establish contact, the therapist's knee will be placed against the participant's flexed knee. A high-velocity, low-amplitude thrust will then be delivered to optimize joint motion, with cavitation being monitored throughout the procedure.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

BASIC_SCIENCE

Masking

DOUBLE (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 55 Years

Healthy volunteers

Inclusion criteria

* Individuals who have undergone anterior cruciate ligament reconstruction * Successful return to recreational sports participation

Exclusion criteria

* Peripheral or central neurological disorders * Systemic or degenerative diseases * History of spinal surgery * Contraindications to spinal manipulation * Low back or sacroiliac pain within the previous month * Prior exposure to manipulative therapy

Design outcomes

Primary

Measure	Time frame
Co-contraction Index	Outcome measures will be assessed at baseline and 10 minutes post-intervention.

Countries

Portugal

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026