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Diagnosis of Wire Syndrome

How to Diagnose Wire Syndrome ? A Classification Based on Retrospective Studies and Clinical Experience

Status
Enrolling by invitation
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07030023
Enrollment
40
Registered
2025-06-19
Start date
2025-03-28
Completion date
2025-07-31
Last updated
2025-06-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orthodontic Wires

Brief summary

The Wire Syndrome (WS) refers to aberrant, unexpected, unexplained, or excessive dental movements involving teeth held by an intact post-orthodontic retention wire. Its prevalence ranging from 1.1% to 43%. It is a chronic, progressive pathological process, generally asymptomatic, resulting in a new malocclusion that is not due to relapse or a physiological process, and whose aesthetic and/or functional dento-periodontal consequences are harmful. The causes are multifactorial origin. In the early stages of Wire Syndrome, dental and periodontal consequences are minors. These issues are thought to progressively worsen over time.However, to date, no author has proposed an appropriate diagnostic approach. Indeed, several diagnostic criteria have been reported in the literature, but their hierarchical ranking, in terms of importance and specificity, has yet to be determined. The main objective of this study is therefore to propose a classification of WS according to its severity, based on a shared framework between periodontists and orthodontists. This classification should, facilitate early detection of the syndrome, and reduce diagnostic delays and therapeutic errors. It should also help clarify prognosis and improve interprofessional collaboration in developing personalized treatment plans.

Interventions

OTHERNon intervention

Non intervention

Sponsors

Centre Hospitalier Universitaire de Nice
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Presence of fixed orthodontic retention (maxillary and/or mandible) * Comprehensive documentation available * Systemically healthy * Presence or not of a Wire Syndrome

Exclusion criteria

* Patient with other orthodontic retention. * Patient unable to understand french

Design outcomes

Primary

MeasureTime frameDescription
Presence of Wire SyndromeAt the inclusionThe presence of Wire Syndrome was clinically evaluated (based on photographs) under 2 answers Yes or No.
severity classification of Wire SyndromeAt the inclusionSeverity was categorized into three grades such as minor, moderate, and severe based on dental and periodontal parameters.

Secondary

MeasureTime frameDescription
Major clinical diagnosis criteria (Fleiss Kappa)At the inclusionFleiss Kappa coefficient : minimum value : \<0 = no aggreeement; maximum value : \> 0.8 = almost perfect.
Minor clinical diagnostis criteria (Fleiss Kappa)At the inclusionFleiss Kappa coefficient : minimum value : \<0 = no aggreeement; maximum value : \> 0.8 = almost perfect.

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 9, 2026